Tumour necrosis factor-alpha gene expression by alveolar macrophages in human lung allograft recipient with recurrence of sarcoidosis. Toulouse Lung Transplantation Group

Recurrence of sarcoidosis in lung allografts is an interesting model to study the pathogenesis of this disease. We report a case of sarcoidosis recurrence in a single lung allograft recipient 2 years after transplantation. The expression of tumour necrosis factor-alpha (TNF-alpha) gene by alveolar m...

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Veröffentlicht in:The European respiratory journal 1996-05, Vol.9 (5), p.1087-1089
Hauptverfasser: Martel, S, Carre, PC, Carrera, G, Pipy, B, Leophonte, PJ
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container_title The European respiratory journal
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creator Martel, S
Carre, PC
Carrera, G
Pipy, B
Leophonte, PJ
description Recurrence of sarcoidosis in lung allografts is an interesting model to study the pathogenesis of this disease. We report a case of sarcoidosis recurrence in a single lung allograft recipient 2 years after transplantation. The expression of tumour necrosis factor-alpha (TNF-alpha) gene by alveolar macrophages was monitored. The TNF-alpha gene was not expressed at the time of recurrence of sarcoidosis, but only later when prominent granulomas were observed.
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source MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Adult
Gene Expression
Graft Rejection
Humans
Lung Transplantation - adverse effects
Macrophages, Alveolar - metabolism
Male
Recurrence
Sarcoidosis - immunology
Sarcoidosis - physiopathology
Sarcoidosis - surgery
Transplantation, Homologous
Tumor Necrosis Factor-alpha - analysis
title Tumour necrosis factor-alpha gene expression by alveolar macrophages in human lung allograft recipient with recurrence of sarcoidosis. Toulouse Lung Transplantation Group
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