Binding preferences of the POU domain protein Brain-4: implications for autoregulation

The POU domain-containing transcription factor Brain-4 (Brn-4, RHS-2) was examined for its sites of expression and DNA binding preferences. In the rat, Brn-4 is expressed in 76 and 65% of vasopressin neurons in the paraventricular and supraoptic nuclei, respectively; but in only 10% of corticotropin...

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Veröffentlicht in:	Brain research. Molecular brain research. 1996-06, Vol.38 (2), p.209-221
Hauptverfasser:	Malik, Karl F., Kim, Jin, Hartman, Adam L., Kim, Paul, Scott Young, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - chemistry Animals Autoregulation Biochemistry and metabolism Biological and medical sciences Central nervous system DNA Footprinting DNA-Binding Proteins - chemistry DNA-Binding Proteins - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Gene regulation Histocytochemistry Homeostasis Hypothalamus In Situ Hybridization Male Mice Mice, Inbred Strains Molecular Sequence Data Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - metabolism Neuropeptide POU POU Domain Factors Promoter Regions, Genetic Protein Binding Protein Structure, Tertiary Rats Rats, Sprague-Dawley Thymine - chemistry Transcription factor Transcription Factors - chemistry Transcription Factors - metabolism Vertebrates: nervous system and sense organs
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