Monitoring Lupus Anticoagulant-Positive Pregnancies With Umbilical Artery Flow Velocity Waveforms
The presence of the “lupus anticoagulant” in maternal blood is associated with thrombosis in the placental vessels and a high rate of fetal loss. We followed six pregnancies in four mothers positive for lupus anticoagulant autoantibody with Doppler umbilical flow studies. The women were not treated...
Gespeichert in:
| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1988-08, Vol.72 (2), p.215-218 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 218 |
|---|---|
| container_issue | 2 |
| container_start_page | 215 |
| container_title | Obstetrics and gynecology (New York. 1953) |
| container_volume | 72 |
| creator | TRUDINGER, BRIAN J STEWART, GRAEME J COOK, COLLEEN M CONNELLY, ANITA EXNER, TOM |
| description | The presence of the “lupus anticoagulant” in maternal blood is associated with thrombosis in the placental vessels and a high rate of fetal loss. We followed six pregnancies in four mothers positive for lupus anticoagulant autoantibody with Doppler umbilical flow studies. The women were not treated with any drugs, and clinical management was guided by close fetal surveillance including umbilical flow studies. Umbilical artery flow velocity waveforms detect vascular abnormalities in the fetal umbilical placental circulation and were used as an early indicator of developing disease. All pregnancies produced live-born infants. These cases indicate the potential value of such studies in the management of this group at high risk of fetal loss. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_78306930</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78306930</sourcerecordid><originalsourceid>FETCH-LOGICAL-p2805-4c1f29adf66dcbfc894e759ff3edc2fc355ff5b97205d2b2b87e72886bfe7ac73</originalsourceid><addsrcrecordid>eNo9kEtLxDAUhYsoOj5-gpCFuCukSdOky2FwVBjRha9dSdObmWjajEnqMP_eiMXV5XI-DnznIJsVgtOcUPp-mM0wJnXORVmeZKchfGCMi6qmx9kxLWhZETHL5IMbTHTeDGu0GrdjQPMhGuXkerRyiPmTCyaab0BPHtaDHJSBgN5M3KCXvjXWKGnR3Efwe7S0bodewTpl4h69yW_QzvfhPDvS0ga4mO5Z9rK8eV7c5avH2_vFfJVvicAsL1WhSS07XVWdarUSdQmc1VpT6BTRijKmNWtrTjDrSEtawYETIapWA5eK07Ps-q93693XCCE2vQkKbNIAN4aGC4qTPE7g5QSObQ9ds_Wml37fTJuk_GrKZUh62v9ah3-MFxWvBU1Y-YftnE3-4dOOO_DNBqSNmyZNjSvCcF7UQmCRvvx3fUZ_APMWfTU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78306930</pqid></control><display><type>article</type><title>Monitoring Lupus Anticoagulant-Positive Pregnancies With Umbilical Artery Flow Velocity Waveforms</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>TRUDINGER, BRIAN J ; STEWART, GRAEME J ; COOK, COLLEEN M ; CONNELLY, ANITA ; EXNER, TOM</creator><creatorcontrib>TRUDINGER, BRIAN J ; STEWART, GRAEME J ; COOK, COLLEEN M ; CONNELLY, ANITA ; EXNER, TOM</creatorcontrib><description>The presence of the “lupus anticoagulant” in maternal blood is associated with thrombosis in the placental vessels and a high rate of fetal loss. We followed six pregnancies in four mothers positive for lupus anticoagulant autoantibody with Doppler umbilical flow studies. The women were not treated with any drugs, and clinical management was guided by close fetal surveillance including umbilical flow studies. Umbilical artery flow velocity waveforms detect vascular abnormalities in the fetal umbilical placental circulation and were used as an early indicator of developing disease. All pregnancies produced live-born infants. These cases indicate the potential value of such studies in the management of this group at high risk of fetal loss.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 3134628</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Autoantibodies - analysis ; Biological and medical sciences ; Blood Coagulation Disorders - blood ; Blood Coagulation Disorders - immunology ; Blood Coagulation Disorders - physiopathology ; Blood Coagulation Factors - blood ; Blood Coagulation Factors - immunology ; Blood Flow Velocity ; Diseases of mother, fetus and pregnancy ; Female ; Fetal Monitoring - methods ; Gestational Age ; Gynecology. Andrology. Obstetrics ; Humans ; Infant, Newborn ; Lupus Coagulation Inhibitor ; Medical sciences ; Phospholipids - blood ; Pregnancy ; Pregnancy Complications, Hematologic - blood ; Pregnancy Complications, Hematologic - immunology ; Pregnancy Complications, Hematologic - physiopathology ; Pregnancy Outcome ; Pregnancy Trimester, Second ; Pregnancy. Fetus. Placenta ; Prenatal Care ; Ultrasonography ; Umbilical Arteries ; Vascular Resistance</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1988-08, Vol.72 (2), p.215-218</ispartof><rights>1988 The American College of Obstetricians and Gynecologists</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7167983$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3134628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>TRUDINGER, BRIAN J</creatorcontrib><creatorcontrib>STEWART, GRAEME J</creatorcontrib><creatorcontrib>COOK, COLLEEN M</creatorcontrib><creatorcontrib>CONNELLY, ANITA</creatorcontrib><creatorcontrib>EXNER, TOM</creatorcontrib><title>Monitoring Lupus Anticoagulant-Positive Pregnancies With Umbilical Artery Flow Velocity Waveforms</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>The presence of the “lupus anticoagulant” in maternal blood is associated with thrombosis in the placental vessels and a high rate of fetal loss. We followed six pregnancies in four mothers positive for lupus anticoagulant autoantibody with Doppler umbilical flow studies. The women were not treated with any drugs, and clinical management was guided by close fetal surveillance including umbilical flow studies. Umbilical artery flow velocity waveforms detect vascular abnormalities in the fetal umbilical placental circulation and were used as an early indicator of developing disease. All pregnancies produced live-born infants. These cases indicate the potential value of such studies in the management of this group at high risk of fetal loss.</description><subject>Autoantibodies - analysis</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation Disorders - blood</subject><subject>Blood Coagulation Disorders - immunology</subject><subject>Blood Coagulation Disorders - physiopathology</subject><subject>Blood Coagulation Factors - blood</subject><subject>Blood Coagulation Factors - immunology</subject><subject>Blood Flow Velocity</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Fetal Monitoring - methods</subject><subject>Gestational Age</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Lupus Coagulation Inhibitor</subject><subject>Medical sciences</subject><subject>Phospholipids - blood</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Hematologic - blood</subject><subject>Pregnancy Complications, Hematologic - immunology</subject><subject>Pregnancy Complications, Hematologic - physiopathology</subject><subject>Pregnancy Outcome</subject><subject>Pregnancy Trimester, Second</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Prenatal Care</subject><subject>Ultrasonography</subject><subject>Umbilical Arteries</subject><subject>Vascular Resistance</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLxDAUhYsoOj5-gpCFuCukSdOky2FwVBjRha9dSdObmWjajEnqMP_eiMXV5XI-DnznIJsVgtOcUPp-mM0wJnXORVmeZKchfGCMi6qmx9kxLWhZETHL5IMbTHTeDGu0GrdjQPMhGuXkerRyiPmTCyaab0BPHtaDHJSBgN5M3KCXvjXWKGnR3Efwe7S0bodewTpl4h69yW_QzvfhPDvS0ga4mO5Z9rK8eV7c5avH2_vFfJVvicAsL1WhSS07XVWdarUSdQmc1VpT6BTRijKmNWtrTjDrSEtawYETIapWA5eK07Ps-q93693XCCE2vQkKbNIAN4aGC4qTPE7g5QSObQ9ds_Wml37fTJuk_GrKZUh62v9ah3-MFxWvBU1Y-YftnE3-4dOOO_DNBqSNmyZNjSvCcF7UQmCRvvx3fUZ_APMWfTU</recordid><startdate>198808</startdate><enddate>198808</enddate><creator>TRUDINGER, BRIAN J</creator><creator>STEWART, GRAEME J</creator><creator>COOK, COLLEEN M</creator><creator>CONNELLY, ANITA</creator><creator>EXNER, TOM</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198808</creationdate><title>Monitoring Lupus Anticoagulant-Positive Pregnancies With Umbilical Artery Flow Velocity Waveforms</title><author>TRUDINGER, BRIAN J ; STEWART, GRAEME J ; COOK, COLLEEN M ; CONNELLY, ANITA ; EXNER, TOM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2805-4c1f29adf66dcbfc894e759ff3edc2fc355ff5b97205d2b2b87e72886bfe7ac73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Autoantibodies - analysis</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation Disorders - blood</topic><topic>Blood Coagulation Disorders - immunology</topic><topic>Blood Coagulation Disorders - physiopathology</topic><topic>Blood Coagulation Factors - blood</topic><topic>Blood Coagulation Factors - immunology</topic><topic>Blood Flow Velocity</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Fetal Monitoring - methods</topic><topic>Gestational Age</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Lupus Coagulation Inhibitor</topic><topic>Medical sciences</topic><topic>Phospholipids - blood</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Hematologic - blood</topic><topic>Pregnancy Complications, Hematologic - immunology</topic><topic>Pregnancy Complications, Hematologic - physiopathology</topic><topic>Pregnancy Outcome</topic><topic>Pregnancy Trimester, Second</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Prenatal Care</topic><topic>Ultrasonography</topic><topic>Umbilical Arteries</topic><topic>Vascular Resistance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TRUDINGER, BRIAN J</creatorcontrib><creatorcontrib>STEWART, GRAEME J</creatorcontrib><creatorcontrib>COOK, COLLEEN M</creatorcontrib><creatorcontrib>CONNELLY, ANITA</creatorcontrib><creatorcontrib>EXNER, TOM</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TRUDINGER, BRIAN J</au><au>STEWART, GRAEME J</au><au>COOK, COLLEEN M</au><au>CONNELLY, ANITA</au><au>EXNER, TOM</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Monitoring Lupus Anticoagulant-Positive Pregnancies With Umbilical Artery Flow Velocity Waveforms</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1988-08</date><risdate>1988</risdate><volume>72</volume><issue>2</issue><spage>215</spage><epage>218</epage><pages>215-218</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>The presence of the “lupus anticoagulant” in maternal blood is associated with thrombosis in the placental vessels and a high rate of fetal loss. We followed six pregnancies in four mothers positive for lupus anticoagulant autoantibody with Doppler umbilical flow studies. The women were not treated with any drugs, and clinical management was guided by close fetal surveillance including umbilical flow studies. Umbilical artery flow velocity waveforms detect vascular abnormalities in the fetal umbilical placental circulation and were used as an early indicator of developing disease. All pregnancies produced live-born infants. These cases indicate the potential value of such studies in the management of this group at high risk of fetal loss.</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>3134628</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 1988-08, Vol.72 (2), p.215-218 |
| issn | 0029-7844 1873-233X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78306930 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Autoantibodies - analysis Biological and medical sciences Blood Coagulation Disorders - blood Blood Coagulation Disorders - immunology Blood Coagulation Disorders - physiopathology Blood Coagulation Factors - blood Blood Coagulation Factors - immunology Blood Flow Velocity Diseases of mother, fetus and pregnancy Female Fetal Monitoring - methods Gestational Age Gynecology. Andrology. Obstetrics Humans Infant, Newborn Lupus Coagulation Inhibitor Medical sciences Phospholipids - blood Pregnancy Pregnancy Complications, Hematologic - blood Pregnancy Complications, Hematologic - immunology Pregnancy Complications, Hematologic - physiopathology Pregnancy Outcome Pregnancy Trimester, Second Pregnancy. Fetus. Placenta Prenatal Care Ultrasonography Umbilical Arteries Vascular Resistance |
| title | Monitoring Lupus Anticoagulant-Positive Pregnancies With Umbilical Artery Flow Velocity Waveforms |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T08%3A56%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Monitoring%20Lupus%20Anticoagulant-Positive%20Pregnancies%20With%20Umbilical%20Artery%20Flow%20Velocity%20Waveforms&rft.jtitle=Obstetrics%20and%20gynecology%20(New%20York.%201953)&rft.au=TRUDINGER,%20BRIAN%20J&rft.date=1988-08&rft.volume=72&rft.issue=2&rft.spage=215&rft.epage=218&rft.pages=215-218&rft.issn=0029-7844&rft.eissn=1873-233X&rft.coden=OBGNAS&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E78306930%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78306930&rft_id=info:pmid/3134628&rfr_iscdi=true |