A cytopathic infectivity assay of human immunodeficiency virus type 1 in human primary macrophages

In addition to CD4 + T lymphocytes, cells of monocyte/macrophage lineage are a major target for human immunodeficiency virus type 1 (HIV-1) infection. In vitro studies of H1V-1 infection in human monocyte-derived macrophages can be undertaken by a reproducible cell-based assay. A macrophage-based in...

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Veröffentlicht in:	Journal of virological methods 1996-05, Vol.59 (1), p.45-55
Hauptverfasser:	Wu, Suh-Chin, Spouge, John L., Merges, Michael J., Conley, Shawn R., Nara, Peter L.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Anti-HIV Agents - pharmacology Biological and medical sciences Cells, Cultured Cytopathogenic Effect, Viral Cytopathology HIV Antigens - analysis HIV Core Protein p24 - analysis HIV-1 HIV-1 - isolation & purification human immunodeficiency virus 1 Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectivity assay Linear Models Macrophages - cytology Macrophages - virology Medical sciences Neutralization Tests Primary macrophage Reproducibility of Results Zidovudine - pharmacology
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