Structural specificity of haemosiderin iron cores in iron-overload diseases

Haemosiderin iron cores isolated from patients with secondary haemochromatosis have a goethite-like (α-FeOOH) crystal structure whereas those from patients with primary haemochromatosis are amorphous Fe (III) oxide. Haemosiderin cores isolated from normal human spleen are crystalline ferrihydrite (5...

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Veröffentlicht in:	FEBS letters 1988-07, Vol.234 (1), p.69-72
Hauptverfasser:	Mann, S., Wade, V.J., Dickson, D.P.E., Reid, N.M.K., Ward, R.J., O'Connell, M., Peters, T.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Crystallization Dialysis Electrophoresis, Polyacrylamide Gel Ferric Compounds Ferritins - analysis Fundamental and applied biological sciences. Psychology hemochromatosis Hemochromatosis - metabolism Hemosiderin Hemosiderin - analysis Humans Iron - analysis Iron - metabolism Iron-core structure Iron-overload Liver - analysis Metalloproteins Microscopy, Electron Other metalloproteins Oxalates Oxalic Acid Proteins Proteins - analysis Solubility Spectrometry, Gamma Spleen - analysis
Online-Zugang:	Volltext
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