Steroid-growth factor interaction in human prostate cancer. 2. Effects of transforming growth factors on androgen metabolism of prostate cancer cells

The ability of human prostate cancer cells to metabolize androgens was assessed through administration of physiological concentration (0.5–10 nM) of tritiated testosterone (T) as precursor and one-step analysis of both T degradation and products' formation by reverse-phase HPLC and on-line radi...

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Veröffentlicht in:Steroids 1996, Vol.61 (1), p.41-46
Hauptverfasser: Carruba, Giuseppe, Granata, Orazia M., Farruggio, Rosaria, Cannella, Sonia, Lo Bue, Arianna, Leake, Robin E., Pavone-Macaluso, Michele, Castagnetta, Luigi A.M.
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