Clinical Utility of Thyrotropin-Receptor Antibody Assays: Comparison of Radioreceptor and Bioassay Methods

Thyrotropin (thyroid-stimulating hormone or TSH)-receptor antibodies, important in the pathogenesis of Graves' disease, can be assayed by one of two methods: (1) bioassays that measure stimulation of thyroid cellular activity by patient immunoglobulins or (2) radioreceptor assays that measure i...

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Veröffentlicht in:	Mayo Clinic proceedings 1988-07, Vol.63 (7), p.707-717
Hauptverfasser:	MORRIS, JOHN C., HAY, IAN D., NELSON, ROBERT E., JIANG, NAI-SIANG
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - analysis Autoantibodies - analysis Biological and medical sciences Biological Assay - standards Cyclic AMP - analysis Endocrinology Evaluation Studies as Topic Eye Diseases - diagnosis Eye Diseases - etiology Eye Diseases - immunology Graves Disease - complications Graves Disease - diagnosis Graves Disease - immunology Humans Hyperparathyroidism, Secondary - diagnosis Hyperparathyroidism, Secondary - etiology Hyperparathyroidism, Secondary - immunology Immunoglobulin G - analysis Immunoglobulins, Thyroid-Stimulating Investigative techniques, diagnostic techniques (general aspects) Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Predictive Value of Tests Radioligand Assay - methods Radioligand Assay - standards Reagent Kits, Diagnostic Receptors, Thyrotropin - immunology Retrospective Studies Thyroid Gland - immunology Time Factors
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