During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium

Localization of activated natural killer (A-NK) cells in the microvasculature of growing tumors is the result of recognition of the intracellular and vascular cell-adhesion molecules ICAM-1 and VCAM-1 on the tumor endothelium, mediated by lymphocyte function-associated protein LFA-1 and vascular lym...

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Veröffentlicht in:	Nature medicine 1996-09, Vol.2 (9), p.992-997
Hauptverfasser:	Melder, R J, Koenig, G C, Witwer, B P, Safabakhsh, N, Munn, L L, Jain, R K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion E-Selectin - physiology Endothelial Growth Factors - physiology Endothelium, Vascular - immunology Fibroblast Growth Factor 2 - physiology Humans Intercellular Adhesion Molecule-1 - physiology Killer Cells, Lymphokine-Activated - immunology Lymphocyte Function-Associated Antigen-1 - physiology Lymphokines - physiology Mice Mice, SCID Neoplasms, Experimental - blood supply Neoplasms, Experimental - etiology Neoplasms, Experimental - immunology Neovascularization, Pathologic - immunology P-Selectin - physiology Tumor Cells, Cultured Vascular Cell Adhesion Molecule-1 - physiology Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors
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