A Gene for Autosomal Dominant Late-Onset Progressive Non-Syndromic Hearing Loss, DFNA10, Maps to Chromosome 6
Late-onset non-syndromic hearing impairment is the most common type of neurological dysfunction in the elderly. It can be either acquired or inherited, although the relative impact of heredity on this type of loss is not known. To date, nine different genes have been localized, but none has been clo...
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| Veröffentlicht in: | Human molecular genetics 1996-06, Vol.5 (6), p.853-856 |
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| container_title | Human molecular genetics |
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| creator | O'Neill, Marsha E. Marietta, Jacquie Nishimura, Darryl Wayne, Sigrid Van Camp, Guy Van Laer, Lut Negrini, Clelia Wilcox, Edward R. Chen, Achih Fukushima, Kunihiro Ni, Li Sheffield, Val C. Smith, Richard J. H. |
| description | Late-onset non-syndromic hearing impairment is the most common type of neurological dysfunction in the elderly. It can be either acquired or inherited, although the relative impact of heredity on this type of loss is not known. To date, nine different genes have been localized, but none has been cloned. Using an extended American family in which a gene for autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a new locus, DFNA10, on chromosome 6. |
| doi_str_mv | 10.1093/hmg/5.6.853 |
| format | Article |
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H.</creatorcontrib><title>A Gene for Autosomal Dominant Late-Onset Progressive Non-Syndromic Hearing Loss, DFNA10, Maps to Chromosome 6</title><title>Human molecular genetics</title><addtitle>Human Molecular Genetics</addtitle><description>Late-onset non-syndromic hearing impairment is the most common type of neurological dysfunction in the elderly. It can be either acquired or inherited, although the relative impact of heredity on this type of loss is not known. To date, nine different genes have been localized, but none has been cloned. Using an extended American family in which a gene for autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a new locus, DFNA10, on chromosome 6.</description><subject>Biological and medical sciences</subject><subject>Chromosome Mapping</subject><subject>Chromosomes, Human, Pair 6</subject><subject>Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology</subject><subject>Female</subject><subject>Genes, Dominant</subject><subject>Hearing Loss, Sensorineural - genetics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. 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| ispartof | Human molecular genetics, 1996-06, Vol.5 (6), p.853-856 |
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| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Biological and medical sciences Chromosome Mapping Chromosomes, Human, Pair 6 Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Female Genes, Dominant Hearing Loss, Sensorineural - genetics Humans Male Medical sciences Middle Aged Non tumoral diseases Otorhinolaryngology. Stomatology Pedigree |
| title | A Gene for Autosomal Dominant Late-Onset Progressive Non-Syndromic Hearing Loss, DFNA10, Maps to Chromosome 6 |
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