Cardiac activation mapping by MRI

To establish cardiac MRI as a tool for noninvasive evaluation of activation patterns, 10 healthy volunteers were examined by cine segmented turboFLASH imaging sequences. Sequence modifications for low signal blood-pool appearance were applied, i.e., bilateral spatial saturation for segmented turboFL...

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Veröffentlicht in:Magma (New York, N.Y.) N.Y.), 1996-03, Vol.4 (1), p.19-25
Hauptverfasser: Knollmann, F D, Mäurer, J, Kücherer, H, Böck, J C, O'Connell, J W, Botvinick, E, Eichstädt, H W, Felix, R
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container_issue 1
container_start_page 19
container_title Magma (New York, N.Y.)
container_volume 4
creator Knollmann, F D
Mäurer, J
Kücherer, H
Böck, J C
O'Connell, J W
Botvinick, E
Eichstädt, H W
Felix, R
description To establish cardiac MRI as a tool for noninvasive evaluation of activation patterns, 10 healthy volunteers were examined by cine segmented turboFLASH imaging sequences. Sequence modifications for low signal blood-pool appearance were applied, i.e., bilateral spatial saturation for segmented turboFLASH imaging. Pixelwise calculation of first-harmonic Fourier phase values (displayed as color-encoded maps) reveal either anterior septal or left ventricular free-wall sites as areas of earliest phase spreading towards posterior paraseptal sites in segmented turboFLASH scans. Phase scatter is lower in unsaturated than spatially presaturated segmented turboFLASH studies. Phase standard deviation in areas of endocardial displacement is higher in basal than apical slice positions in these scans. Early results indicate that first-harmonic Fourier phase analysis of cardiac-segmented turboFLASH MRI cine studies may provide a tool for noninvasive studies of cardiac activation sequence.
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subjects Adult
Aged
Female
Fourier Analysis
Heart - anatomy & histology
Heart - physiology
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging, Cine - methods
Male
Middle Aged
title Cardiac activation mapping by MRI
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