Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

Various inhibitors were tested for their potential to suppress the kinase activity of protein kinase C mu (PKC mu) in vitro and in vivo. Among the staurosporine-derived, rather selective PKC inhibitors the indolocarbazole Gö 6976 previously shown to inhibit preferentially cPKC isotypes proved to be...

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Veröffentlicht in:FEBS letters 1996-08, Vol.392 (2), p.77-80
Hauptverfasser: Gschwendt, M, Dieterich, S, Rennecke, J, Kittstein, W, Mueller, H J, Johannes, F J
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Sprache:eng
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