In vitro effects of eicosanoid synthesis inhibitors in the presence of linoleic acid on MDA-MB-231 human breast cancer cells

We investigated the effects of cyclooxygenase and lipoxygenase inhibitors in the presence of linoleic acid (LA), as well as the direct effects of prostaglandin E (PGE) and leukotriene B (LTB) on a human breast cancer cell line (MDA-MB-231) in vitro. Piroxicam, esculetin, and nordihydroguaiaretic aci...

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Veröffentlicht in:	Breast cancer research and treatment 1996, Vol.37 (1), p.29-37
Hauptverfasser:	EARASHI, M, NOGUCHI, M, TANAKA, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Division - drug effects Cyclooxygenase Inhibitors - pharmacology Dinoprostone - metabolism Dinoprostone - pharmacology Drug toxicity and drugs side effects treatment Female Humans Leukotriene B4 - metabolism Leukotriene B4 - pharmacology Linoleic Acid Linoleic Acids - pharmacology Lipoxygenase Inhibitors - pharmacology Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Pharmacology. Drug treatments Tumor Cells, Cultured
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