Analysis of the functional domains of biosynthetic threonine deaminase by comparison of the amino acid sequences of three wild-type alleles to the amino acid sequence of biodegradative threonine deaminase

The nucleotide sequence of the gene, ilvA, for biosynthetic threonine deaminase (Tda) from Salmonella typhimurium was determined. The deduced amino acid sequence was compared with the deduced amino acid sequences of the biosynthetic Tda from Escherichia coli K-12 (ilvA) and Saccharomyces cerevisiae...

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Veröffentlicht in:	Gene 1988-03, Vol.63 (2), p.245-252
Hauptverfasser:	Taillon, Bruce E., Little, Robert, Lawther, Robert P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles allosteric regulation Amino Acid Sequence Analytical, structural and metabolic biochemistry Base Sequence Biological and medical sciences Biology of microorganisms of confirmed or potential industrial interest Biotechnology Enzymes and enzyme inhibitors Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli K-12 feedback inhibition Fundamental and applied biological sciences. Psychology Genes Genes, Bacterial genes, ilvA, ILV1, tdc Isoenzymes - genetics Isoenzymes - metabolism isozymes Lyases Mission oriented research Molecular Sequence Data Physiology and metabolism Recombinant DNA Saccharomyces cerevisiae Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Salmonella typhimurium Salmonella typhimurium - enzymology Salmonella typhimurium - genetics Species Specificity Threonine Dehydratase - genetics Threonine Dehydratase - metabolism
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