The amino acid substitution in albumin Roma: 321 Glu → Lys

Albumin Roma is an electrophoretically slow moving genetic variant of human serum albumin found in 22 unrelated families. The protein was isolated from the serum of a healthy, heterozygous subject. Analysis of CNBr fragments by isoelectric focusing allowed us to localize the mutation to fragment CNB...

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Veröffentlicht in:	FEBS letters 1988-06, Vol.233 (1), p.100-104
Hauptverfasser:	Galliano, M., Minchiotti, L., Iadarola, P., Ferri, G., Zapponi, M.C., Castellani, A.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Biological and medical sciences Chromatography, High Pressure Liquid Chromatography, Ion Exchange Cyanogen Bromide Fundamental and applied biological sciences. Psychology Genetic variant Glutamates Glutamic Acid Heterozygote Holoproteins HPLC Human serum albumin Humans Hydrogen-Ion Concentration Isoelectric Focusing Lysine Male Mutation Other proteins Peptide Fragments - isolation & purification Proteins Serum Albumin - genetics Serum Albumin - isolation & purification Serum Albumin, Human Trypsin
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