Particle-mediated nucleic acid immunization

Nucleic acid immunization involves the direct in vivo administration of antigen-encoding plasmid DNA molecules that results in the de novo production of correctly folded microbial antigens at the site of DNA delivery. While this process can lead to the development of neutralizing antibody responses...

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of biotechnology 1996-01, Vol.44 (1), p.37-42
Hauptverfasser:	Haynes, Joel R., McCabe, Dennis E., Swain, William F., Widera, Georg, Fuller, James T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation Antigenic determinants, haptens, artificial antigens Antigens Antigens - biosynthesis Antigens - immunology Biological and medical sciences Biotechnology DNA - administration & dosage DNA - metabolism DNA vaccine Epitopes - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Gene gun Genetic Therapy Haplorhini HIV human immunodeficiency virus Humans Immunization - instrumentation Immunization - methods Influenza influenza virus Injections, Intradermal Molecular immunology Nucleic acid vaccine Pig Plasmids - administration & dosage Rhesus monkey Rodentia Swine
Online-Zugang:	Volltext
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