Computer-assisted semen analysis parameters in men with varicocele: is surgery helpful?
To assess sperm characteristics and fertility before and after varicocelectomy using computer-assisted semen analysis (CASA). Preoperative and postoperative sperm parameters of infertile men with varicocele were analyzed statistically and the outcome of pregnancy was determined. Department of Infert...
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Veröffentlicht in: | Fertility and sterility 1996-09, Vol.66 (3), p.440-445 |
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creator | Parikh, Firuza R. Kamat, Sudesh A. Kodwaney, Geeta G. Balaiah, Donta |
description | To assess sperm characteristics and fertility before and after varicocelectomy using computer-assisted semen analysis (CASA).
Preoperative and postoperative sperm parameters of infertile men with varicocele were analyzed statistically and the outcome of pregnancy was determined.
Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay.
Semen samples of 49 men with varicocele-related infertility were analyzed using CASA.
Sperm parameters of 26 men who underwent varicocelectomy were evaluated 3, 6, and 9 months postoperatively. Conception, occurring either naturally or therapeutically, was recorded.
Evaluation of improvement of sperm parameters after surgery.
Sperm count, motility parameters, curvilinear velocity, straightline velocity, lateral head displacement, and normal morphology were significantly lower in men with varicocele. Postoperatively, there was significant improvement in count, motility, and normal morphology, with a decrease in proportion of acrosome-deficient heads and tapering forms. After varicocelectomy, 46.2% of the men had normal semen parameters, with the overall pregnancy rate being 50%.
Computer-assisted semen analysis provides the potential for accurate quantitative evaluation of semen in men with varicocele. Varicocelectomy results in improvement in semen quality with pregnancy rates of 50%. |
doi_str_mv | 10.1016/S0015-0282(16)58516-1 |
format | Article |
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Preoperative and postoperative sperm parameters of infertile men with varicocele were analyzed statistically and the outcome of pregnancy was determined.
Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay.
Semen samples of 49 men with varicocele-related infertility were analyzed using CASA.
Sperm parameters of 26 men who underwent varicocelectomy were evaluated 3, 6, and 9 months postoperatively. Conception, occurring either naturally or therapeutically, was recorded.
Evaluation of improvement of sperm parameters after surgery.
Sperm count, motility parameters, curvilinear velocity, straightline velocity, lateral head displacement, and normal morphology were significantly lower in men with varicocele. Postoperatively, there was significant improvement in count, motility, and normal morphology, with a decrease in proportion of acrosome-deficient heads and tapering forms. After varicocelectomy, 46.2% of the men had normal semen parameters, with the overall pregnancy rate being 50%.
Computer-assisted semen analysis provides the potential for accurate quantitative evaluation of semen in men with varicocele. Varicocelectomy results in improvement in semen quality with pregnancy rates of 50%.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/S0015-0282(16)58516-1</identifier><identifier>PMID: 8751745</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acrosome - ultrastructure ; Adult ; Biological and medical sciences ; Birth control ; CASA ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Image Processing, Computer-Assisted - standards ; infertility ; Infertility, Male - etiology ; Infertility, Male - pathology ; Infertility, Male - physiopathology ; Male ; Medical sciences ; Pregnancy ; Pregnancy Rate ; Semen - cytology ; Semen - physiology ; Sperm Count ; Sperm Motility - physiology ; Spermatozoa - cytology ; Spermatozoa - physiology ; Spermatozoa - ultrastructure ; Sterility. Assisted procreation ; Varicocele ; Varicocele - complications ; Varicocele - pathology ; Varicocele - physiopathology ; Varicocele - surgery</subject><ispartof>Fertility and sterility, 1996-09, Vol.66 (3), p.440-445</ispartof><rights>1996 American Society for Reproductive Medicine</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-7392c1bbbb4891ba194ded0e0b4a75d91f70c97332759ad1effdfe3fa419493</citedby><cites>FETCH-LOGICAL-c436t-7392c1bbbb4891ba194ded0e0b4a75d91f70c97332759ad1effdfe3fa419493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0015028216585161$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3207286$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8751745$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Parikh, Firuza R.</creatorcontrib><creatorcontrib>Kamat, Sudesh A.</creatorcontrib><creatorcontrib>Kodwaney, Geeta G.</creatorcontrib><creatorcontrib>Balaiah, Donta</creatorcontrib><title>Computer-assisted semen analysis parameters in men with varicocele: is surgery helpful?</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>To assess sperm characteristics and fertility before and after varicocelectomy using computer-assisted semen analysis (CASA).
Preoperative and postoperative sperm parameters of infertile men with varicocele were analyzed statistically and the outcome of pregnancy was determined.
Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay.
Semen samples of 49 men with varicocele-related infertility were analyzed using CASA.
Sperm parameters of 26 men who underwent varicocelectomy were evaluated 3, 6, and 9 months postoperatively. Conception, occurring either naturally or therapeutically, was recorded.
Evaluation of improvement of sperm parameters after surgery.
Sperm count, motility parameters, curvilinear velocity, straightline velocity, lateral head displacement, and normal morphology were significantly lower in men with varicocele. Postoperatively, there was significant improvement in count, motility, and normal morphology, with a decrease in proportion of acrosome-deficient heads and tapering forms. After varicocelectomy, 46.2% of the men had normal semen parameters, with the overall pregnancy rate being 50%.
Computer-assisted semen analysis provides the potential for accurate quantitative evaluation of semen in men with varicocele. Varicocelectomy results in improvement in semen quality with pregnancy rates of 50%.</description><subject>Acrosome - ultrastructure</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>CASA</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - standards</subject><subject>infertility</subject><subject>Infertility, Male - etiology</subject><subject>Infertility, Male - pathology</subject><subject>Infertility, Male - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy Rate</subject><subject>Semen - cytology</subject><subject>Semen - physiology</subject><subject>Sperm Count</subject><subject>Sperm Motility - physiology</subject><subject>Spermatozoa - cytology</subject><subject>Spermatozoa - physiology</subject><subject>Spermatozoa - ultrastructure</subject><subject>Sterility. Assisted procreation</subject><subject>Varicocele</subject><subject>Varicocele - complications</subject><subject>Varicocele - pathology</subject><subject>Varicocele - physiopathology</subject><subject>Varicocele - surgery</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1r3DAQhkVoSbZpfkLAh1Dag1uNZUl2LyEs_YJADynkKLTSKFHwVzR2yv77arPLXqvLoHmfkYaHsUvgn4GD-nLHOciSV031EdQn2UhQJZywFUipSqmkeMNWR-SMvSN64pwr0NUpO220BF3LFbtfj_20zJhKSxRpRl8Q9jgUdrDdNneKySbbYyaoiEOxi_7G-bF4sSm60WGHX4tM0ZIeMG2LR-ymsHTX79nbYDvCi0M9Z3ffv_1Z_yxvf__4tb65LV0t1Fxq0VYONvnUTQsbC23t0XPkm9pq6VsImrtWC1Fp2VoPGIIPKIKtM9mKc_Zh_-qUxucFaTZ9pLxTZwccFzK6qRSXrcig3IMujUQJg5lS7G3aGuBmp9O86jQ7VybfXnUayHOXhw-WTY_-OHXwl_OrQ27J2S4kO7hIR0xUXFeNytj1HsOs4iViMuQiDg59TOhm48f4n0X-AbD3koY</recordid><startdate>19960901</startdate><enddate>19960901</enddate><creator>Parikh, Firuza R.</creator><creator>Kamat, Sudesh A.</creator><creator>Kodwaney, Geeta G.</creator><creator>Balaiah, Donta</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19960901</creationdate><title>Computer-assisted semen analysis parameters in men with varicocele: is surgery helpful?</title><author>Parikh, Firuza R. ; Kamat, Sudesh A. ; Kodwaney, Geeta G. ; Balaiah, Donta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-7392c1bbbb4891ba194ded0e0b4a75d91f70c97332759ad1effdfe3fa419493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Acrosome - ultrastructure</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>CASA</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - standards</topic><topic>infertility</topic><topic>Infertility, Male - etiology</topic><topic>Infertility, Male - pathology</topic><topic>Infertility, Male - physiopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy Rate</topic><topic>Semen - cytology</topic><topic>Semen - physiology</topic><topic>Sperm Count</topic><topic>Sperm Motility - physiology</topic><topic>Spermatozoa - cytology</topic><topic>Spermatozoa - physiology</topic><topic>Spermatozoa - ultrastructure</topic><topic>Sterility. Assisted procreation</topic><topic>Varicocele</topic><topic>Varicocele - complications</topic><topic>Varicocele - pathology</topic><topic>Varicocele - physiopathology</topic><topic>Varicocele - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parikh, Firuza R.</creatorcontrib><creatorcontrib>Kamat, Sudesh A.</creatorcontrib><creatorcontrib>Kodwaney, Geeta G.</creatorcontrib><creatorcontrib>Balaiah, Donta</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Parikh, Firuza R.</au><au>Kamat, Sudesh A.</au><au>Kodwaney, Geeta G.</au><au>Balaiah, Donta</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Computer-assisted semen analysis parameters in men with varicocele: is surgery helpful?</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>1996-09-01</date><risdate>1996</risdate><volume>66</volume><issue>3</issue><spage>440</spage><epage>445</epage><pages>440-445</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>To assess sperm characteristics and fertility before and after varicocelectomy using computer-assisted semen analysis (CASA).
Preoperative and postoperative sperm parameters of infertile men with varicocele were analyzed statistically and the outcome of pregnancy was determined.
Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay.
Semen samples of 49 men with varicocele-related infertility were analyzed using CASA.
Sperm parameters of 26 men who underwent varicocelectomy were evaluated 3, 6, and 9 months postoperatively. Conception, occurring either naturally or therapeutically, was recorded.
Evaluation of improvement of sperm parameters after surgery.
Sperm count, motility parameters, curvilinear velocity, straightline velocity, lateral head displacement, and normal morphology were significantly lower in men with varicocele. Postoperatively, there was significant improvement in count, motility, and normal morphology, with a decrease in proportion of acrosome-deficient heads and tapering forms. After varicocelectomy, 46.2% of the men had normal semen parameters, with the overall pregnancy rate being 50%.
Computer-assisted semen analysis provides the potential for accurate quantitative evaluation of semen in men with varicocele. Varicocelectomy results in improvement in semen quality with pregnancy rates of 50%.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8751745</pmid><doi>10.1016/S0015-0282(16)58516-1</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Acrosome - ultrastructure Adult Biological and medical sciences Birth control CASA Female Gynecology. Andrology. Obstetrics Humans Image Processing, Computer-Assisted - standards infertility Infertility, Male - etiology Infertility, Male - pathology Infertility, Male - physiopathology Male Medical sciences Pregnancy Pregnancy Rate Semen - cytology Semen - physiology Sperm Count Sperm Motility - physiology Spermatozoa - cytology Spermatozoa - physiology Spermatozoa - ultrastructure Sterility. Assisted procreation Varicocele Varicocele - complications Varicocele - pathology Varicocele - physiopathology Varicocele - surgery |
title | Computer-assisted semen analysis parameters in men with varicocele: is surgery helpful? |
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