Adjuvant‐induced polyarthritis. synovial cell activation prior to polyarthritis onset

We studied synoviocytes obtained from rats that had been injected with Freund's complete adjuvant 12 days prior to killing. We found that several activation parameters were affected in these synoviocytes, namely, the concanavalin A protein‐binding pattern, the production of superoxide, and the...

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Veröffentlicht in:	Arthritis and rheumatism 1988-06, Vol.31 (6), p.769-775
Hauptverfasser:	López‐Bote, Juan Pedro, Bernabeu, Carmelo, Marquet, Alberto, Fernández, Jesús M., Larraga, Vicente
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis - etiology Arthritis, Experimental - etiology Biological and medical sciences Concanavalin A - analogs & derivatives Concanavalin A - metabolism Diseases of the osteoarticular system Fluorescein-5-isothiocyanate - analogs & derivatives Fluoresceins - metabolism Glycoproteins - metabolism Histocompatibility Antigens Class II - immunology Inflammatory joint diseases Iodine Radioisotopes Medical sciences Superoxides - biosynthesis Synovial Membrane - immunology Synovial Membrane - pathology Synovial Membrane - physiology
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