Serum amino acid levels in leukemic mice after l-asparaginase treatment

A rapid, reproducible HPLC method based on dansyl chloride derivatization has been developed for the determination of l-asparagine, l-aspartate, l-glutamine, and l-glutamate in mouse and human serum samples. This improved procedure has been designed for automation with an autoinjector system. Studie...

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Veröffentlicht in:	Biochemical medicine and metabolic biology 1988-04, Vol.39 (2), p.199-207
Hauptverfasser:	Woodward, Christopher N., Sur, Pratima, Capizzi, Robert L., Modest, Edward J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - blood Animals Antineoplastic agents Asparaginase - therapeutic use Biological and medical sciences Chemotherapy Chromatography, High Pressure Liquid - methods Dansyl Compounds - analysis Leukemia, Experimental - blood Leukemia, Experimental - drug therapy Male Medical sciences Mice Mice, Inbred Strains Pharmacology. Drug treatments
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