Significance of cardiac weight in patients having coronary artery bypass grafting for angina pectoris

Cardiac weight at necropsy in 211 patients who had coronary artery bypass grafting (CABG) for angina pectoris, and its relation to early (60 days) death after CABG was sought. The 121 patients dying early had a lower mean heart weight than did the 90 patients dying late (444 ± 94 vs 498 ± 107 g; p :...

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Veröffentlicht in:The American journal of cardiology 1988-07, Vol.62 (1), p.36-40
Hauptverfasser: Kalan, Jay M., Roberts, William C.
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container_title The American journal of cardiology
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Roberts, William C.
description Cardiac weight at necropsy in 211 patients who had coronary artery bypass grafting (CABG) for angina pectoris, and its relation to early (60 days) death after CABG was sought. The 121 patients dying early had a lower mean heart weight than did the 90 patients dying late (444 ± 94 vs 498 ± 107 g; p :0.001). The mean heart weight of the 85 men dying early was less than that of the 75 men dying late (472 vs 506 g; p
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The 121 patients dying early had a lower mean heart weight than did the 90 patients dying late (444 ± 94 vs 498 ± 107 g; p :0.001). The mean heart weight of the 85 men dying early was less than that of the 75 men dying late (472 vs 506 g; p &lt;0.05), and the mean heart weight of the 36 women dying early was less than that of the 15 women dying late (377 vs 459 g; p &lt;0.005). Most patients with hearts of normal weight were in the early death group: of the 17 women with hearts of normal weight (⩽350 g), 16 (94%) died early (p &lt;0.01), and of the 34 men with hearts of normal weight (⩽400 g), 21 (62%) died early (difference not significant). Conversely, most patients in the late death group had hearts of increased weight: of the 15 women dying late, 14 (93%) had hearts of increased weight, and of the 75 men dying late, 62 (83%) had hearts of increased weight. The mean cardiac weight of the 125 patients with left ventricular scars was larger than that of the 86 patients without scars (492 vs 432 g; p &lt;0.01), and these differences were observed within each sex and in both early (463 vs 425 g) and late (520 vs 448 g) death groups. This study suggests that patients with normal or near normal sized hearts have a higher early mortality after CABG than do persons with hearts of increased weight.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/0002-9149(88)91361-6</identifier><identifier>PMID: 3260064</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Angina Pectoris - mortality ; Angina Pectoris - pathology ; Angina Pectoris - surgery ; Biological and medical sciences ; Cardiology. 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The 121 patients dying early had a lower mean heart weight than did the 90 patients dying late (444 ± 94 vs 498 ± 107 g; p :0.001). The mean heart weight of the 85 men dying early was less than that of the 75 men dying late (472 vs 506 g; p &lt;0.05), and the mean heart weight of the 36 women dying early was less than that of the 15 women dying late (377 vs 459 g; p &lt;0.005). Most patients with hearts of normal weight were in the early death group: of the 17 women with hearts of normal weight (⩽350 g), 16 (94%) died early (p &lt;0.01), and of the 34 men with hearts of normal weight (⩽400 g), 21 (62%) died early (difference not significant). Conversely, most patients in the late death group had hearts of increased weight: of the 15 women dying late, 14 (93%) had hearts of increased weight, and of the 75 men dying late, 62 (83%) had hearts of increased weight. The mean cardiac weight of the 125 patients with left ventricular scars was larger than that of the 86 patients without scars (492 vs 432 g; p &lt;0.01), and these differences were observed within each sex and in both early (463 vs 425 g) and late (520 vs 448 g) death groups. This study suggests that patients with normal or near normal sized hearts have a higher early mortality after CABG than do persons with hearts of increased weight.</description><subject>Adult</subject><subject>Aged</subject><subject>Angina Pectoris - mortality</subject><subject>Angina Pectoris - pathology</subject><subject>Angina Pectoris - surgery</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Cause of Death</subject><subject>Coronary Artery Bypass</subject><subject>Coronary heart disease</subject><subject>Female</subject><subject>Heart</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardium - pathology</subject><subject>Organ Size</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1v1DAQhi1EVZbCPwDJB0BwCHjy4TgXJFTxUalSD8DZmtjj1GjXDna2Vf89DrvaYy8ejeaZV_Zjxl6B-AgC5CchRF0N0A7vlfowQCOhkk_YBlQ_VFD6p2xzQp6x5zn_KS1AJ8_ZeVNLIWS7YfTTT8E7bzAY4tFxg8l6NPye_HS7cB_4jIunsGR-i3c-TNzEFAOmB45poVLGhxlz5lNCt6xzFxPHMPmAfCazxOTzC3bmcJvp5bFesN_fvv66_FFd33y_uvxyXZkW5FJZkqbpeiGUkMOIgF3jRlnL0So0SlkoR9OKfnCjolHYcahr0TiwtexKgGwu2LtD7pzi3z3lRe98NrTdYqC4z7pXdQeyWcH2AJoUc07k9Jz8rjxKg9CrXb2q06s6rZT-b1eva6-P-ftxR_a0dNRZ5m-Oc8wGty4Vqz6fsL6vu7ZdY94-hsHQyb6HrnCfDxwVZ3eeks6mfIUh61Mxq230j9_3H1f3o0k</recordid><startdate>19880701</startdate><enddate>19880701</enddate><creator>Kalan, Jay M.</creator><creator>Roberts, William C.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19880701</creationdate><title>Significance of cardiac weight in patients having coronary artery bypass grafting for angina pectoris</title><author>Kalan, Jay M. ; Roberts, William C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-de6c357008069ba1a53fb626bd8ac88d1c8834079fb8eb0db92203f1d26541663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Angina Pectoris - mortality</topic><topic>Angina Pectoris - pathology</topic><topic>Angina Pectoris - surgery</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Cause of Death</topic><topic>Coronary Artery Bypass</topic><topic>Coronary heart disease</topic><topic>Female</topic><topic>Heart</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardium - pathology</topic><topic>Organ Size</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kalan, Jay M.</creatorcontrib><creatorcontrib>Roberts, William C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kalan, Jay M.</au><au>Roberts, William C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Significance of cardiac weight in patients having coronary artery bypass grafting for angina pectoris</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1988-07-01</date><risdate>1988</risdate><volume>62</volume><issue>1</issue><spage>36</spage><epage>40</epage><pages>36-40</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Cardiac weight at necropsy in 211 patients who had coronary artery bypass grafting (CABG) for angina pectoris, and its relation to early (&lt;60 days) and late (&gt;60 days) death after CABG was sought. The 121 patients dying early had a lower mean heart weight than did the 90 patients dying late (444 ± 94 vs 498 ± 107 g; p :0.001). The mean heart weight of the 85 men dying early was less than that of the 75 men dying late (472 vs 506 g; p &lt;0.05), and the mean heart weight of the 36 women dying early was less than that of the 15 women dying late (377 vs 459 g; p &lt;0.005). Most patients with hearts of normal weight were in the early death group: of the 17 women with hearts of normal weight (⩽350 g), 16 (94%) died early (p &lt;0.01), and of the 34 men with hearts of normal weight (⩽400 g), 21 (62%) died early (difference not significant). Conversely, most patients in the late death group had hearts of increased weight: of the 15 women dying late, 14 (93%) had hearts of increased weight, and of the 75 men dying late, 62 (83%) had hearts of increased weight. The mean cardiac weight of the 125 patients with left ventricular scars was larger than that of the 86 patients without scars (492 vs 432 g; p &lt;0.01), and these differences were observed within each sex and in both early (463 vs 425 g) and late (520 vs 448 g) death groups. This study suggests that patients with normal or near normal sized hearts have a higher early mortality after CABG than do persons with hearts of increased weight.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3260064</pmid><doi>10.1016/0002-9149(88)91361-6</doi><tpages>5</tpages></addata></record>
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ispartof The American journal of cardiology, 1988-07, Vol.62 (1), p.36-40
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adult
Aged
Angina Pectoris - mortality
Angina Pectoris - pathology
Angina Pectoris - surgery
Biological and medical sciences
Cardiology. Vascular system
Cause of Death
Coronary Artery Bypass
Coronary heart disease
Female
Heart
Humans
Male
Medical sciences
Middle Aged
Myocardium - pathology
Organ Size
title Significance of cardiac weight in patients having coronary artery bypass grafting for angina pectoris
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