Effect of Pulse on Iontophoretic Delivery of Desmopressin Acetate in Rats

The effect of pulse parameters (duty and frequency) in a constant direct current iontophoresis on the antidiuretic response (elevation in rat urinary osmotic pressure) of desmopressin acetate (DDAVP) was examined in diabetes insipidus rats. Although antidiuretic response was not affected by frequenc...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 1996/05/15, Vol.19(5), pp.738-740
Hauptverfasser:	NAKAKURA, Masashi, KATO, Yasuki, HAYAKAWA, Eiji, ITO, Kunio, KURODA, Tokuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Deamino Arginine Vasopressin - administration & dosage Deamino Arginine Vasopressin - pharmacology desmopressin acetate Diabetes Insipidus - physiopathology Disease Models, Animal Diuresis - drug effects Dose-Response Relationship, Drug Electricity Hormones. Endocrine system Iontophoresis Male Medical sciences Pharmacology. Drug treatments pulse current Rats Rats, Wistar Renal Agents - pharmacology Skin Absorption skin premeability
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