Light-Addressable Potentiometric Sensor for Biochemical Systems

Light-Addressable Potentiometric Sensor for Biochemical Systems

Numerous biochemical reactions can be measured potentiometrically through changes in pH, redox potential, or transmembrane potential. An alternating photocurrent through an electrolyte-insulator-semiconductor interface provides a highly sensitive means to measure such potential changes. A spatially...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1988-05, Vol.240 (4856), p.1182-1185
Hauptverfasser: Hafeman, Dean G., Parce, J. Wallace, McConnell, Harden M.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biophysics
Electric current
Electricity
Electrodes
Electrolytes
Enzymes
Hydrogen-Ion Concentration
Light
Membrane Potentials
Methods
Oxidation-Reduction
Oxynitrides
Potentiometry
Semiconductors
Sensors
Silicon
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Beschreibung
Zusammenfassung:Numerous biochemical reactions can be measured potentiometrically through changes in pH, redox potential, or transmembrane potential. An alternating photocurrent through an electrolyte-insulator-semiconductor interface provides a highly sensitive means to measure such potential changes. A spatially selectable photoresponse permits the determination of a multiplicity of chemical events with a single semiconductor device.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.3375810