Rectal carcinoma: Prospective comparison of conventional and gadopentetate dimeglumine enhanced fat-suppressed MR imaging
The purpose of this study is to compare the usefulness of conventional MR imaging and gadopentetate dimeglumine enhanced fat‐suppressed MR imaging for the depiction and staging of rectal carcinoma. Thirty‐two patients were prospectively evaluated by MR imaging using a 1.5‐T unit. Based on the result...
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Veröffentlicht in: | Journal of magnetic resonance imaging 1996-05, Vol.6 (3), p.465-471 |
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description | The purpose of this study is to compare the usefulness of conventional MR imaging and gadopentetate dimeglumine enhanced fat‐suppressed MR imaging for the depiction and staging of rectal carcinoma. Thirty‐two patients were prospectively evaluated by MR imaging using a 1.5‐T unit. Based on the results of a barium study and/or digital examination, a balloon catheter was inserted to the level of the lesion before examination. Both conventional T1‐ and T2‐weighted images and gadopentetate dimeglumine enhanced fat‐suppressed T1‐weighted images were obtained for all patients. The kappa statistics were performed for the evaluation of interobserver agreement and the McNemar test was performed for the analysis of staging accuracy. When only T1‐ and T2‐weighted images were used, 5 of 32 tumors were not detected and the extent of 18 of 32 tumors were unclear. However, when gadopentetate dimeglumine enhanced fat‐suppressed imaging was added, 24 of 32 tumors were well defined and only one tumor was not detected. In determining the depth of invasion, the staging accuracy was 72% for conventional imaging and 68% for all images combined. There was no significant difference between with gadopentetate dimeglumine fat‐suppressed imaging and conventional imaging (P > .05). Use of gadopentetate dimeglumine (fat‐suppressed imaging) resulted in overestimation of muscular invasion, peri‐rectal fat invasion, and adjacent organ invasion in 12 patients, whereas nine patients were overestimated without the use of gadopentetate dimeglumine. In the detection of metastatic lymph nodes, gadopentetate dimeglumine enhanced fat‐suppressed imaging also was not useful. Tumor detection was excellent using gadopentetate dimeglumine enhanced fat‐suppressed images. However, the accuracy of staging was not improved by obtaining such images. |
doi_str_mv | 10.1002/jmri.1880060309 |
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Thirty‐two patients were prospectively evaluated by MR imaging using a 1.5‐T unit. Based on the results of a barium study and/or digital examination, a balloon catheter was inserted to the level of the lesion before examination. Both conventional T1‐ and T2‐weighted images and gadopentetate dimeglumine enhanced fat‐suppressed T1‐weighted images were obtained for all patients. The kappa statistics were performed for the evaluation of interobserver agreement and the McNemar test was performed for the analysis of staging accuracy. When only T1‐ and T2‐weighted images were used, 5 of 32 tumors were not detected and the extent of 18 of 32 tumors were unclear. However, when gadopentetate dimeglumine enhanced fat‐suppressed imaging was added, 24 of 32 tumors were well defined and only one tumor was not detected. In determining the depth of invasion, the staging accuracy was 72% for conventional imaging and 68% for all images combined. There was no significant difference between with gadopentetate dimeglumine fat‐suppressed imaging and conventional imaging (P > .05). Use of gadopentetate dimeglumine (fat‐suppressed imaging) resulted in overestimation of muscular invasion, peri‐rectal fat invasion, and adjacent organ invasion in 12 patients, whereas nine patients were overestimated without the use of gadopentetate dimeglumine. In the detection of metastatic lymph nodes, gadopentetate dimeglumine enhanced fat‐suppressed imaging also was not useful. Tumor detection was excellent using gadopentetate dimeglumine enhanced fat‐suppressed images. However, the accuracy of staging was not improved by obtaining such images.</description><identifier>ISSN: 1053-1807</identifier><identifier>EISSN: 1522-2586</identifier><identifier>DOI: 10.1002/jmri.1880060309</identifier><identifier>PMID: 8724412</identifier><language>eng</language><publisher>Baltimore: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adipose Tissue - pathology ; Aged ; Aged, 80 and over ; Biopsy ; Colon ; Colon, MR studies ; Colon, neoplasms ; Contrast Media ; Drug Combinations ; Female ; Gadolinium DTPA ; Humans ; Image Enhancement - instrumentation ; Image Processing, Computer-Assisted - instrumentation ; Lymph Nodes - pathology ; Lymphatic Metastasis ; Magnetic Resonance Imaging - instrumentation ; Male ; Meglumine ; Middle Aged ; MR studies ; Neoplasm Invasiveness ; Neoplasm Staging ; neoplasms ; Organometallic Compounds ; Pentetic Acid - analogs & derivatives ; Prospective Studies ; Rectal Neoplasms - diagnosis ; Rectal Neoplasms - pathology ; Rectum - pathology ; Rectum MR studies ; Rectum neoplasms</subject><ispartof>Journal of magnetic resonance imaging, 1996-05, Vol.6 (3), p.465-471</ispartof><rights>Copyright © 1996 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4489-c2edc25692837d63411557c3bedc35ae5ee24c8dd0dc30587613f8babfa793643</citedby><cites>FETCH-LOGICAL-c4489-c2edc25692837d63411557c3bedc35ae5ee24c8dd0dc30587613f8babfa793643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjmri.1880060309$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjmri.1880060309$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8724412$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Okizuka, Hiromi</creatorcontrib><creatorcontrib>Sugimura, Kazuro</creatorcontrib><creatorcontrib>Yoshizako, Takeshi</creatorcontrib><creatorcontrib>Kaji, Yasushi</creatorcontrib><creatorcontrib>Wada, Akihiko</creatorcontrib><title>Rectal carcinoma: Prospective comparison of conventional and gadopentetate dimeglumine enhanced fat-suppressed MR imaging</title><title>Journal of magnetic resonance imaging</title><addtitle>J. Magn. Reson. Imaging</addtitle><description>The purpose of this study is to compare the usefulness of conventional MR imaging and gadopentetate dimeglumine enhanced fat‐suppressed MR imaging for the depiction and staging of rectal carcinoma. Thirty‐two patients were prospectively evaluated by MR imaging using a 1.5‐T unit. Based on the results of a barium study and/or digital examination, a balloon catheter was inserted to the level of the lesion before examination. Both conventional T1‐ and T2‐weighted images and gadopentetate dimeglumine enhanced fat‐suppressed T1‐weighted images were obtained for all patients. The kappa statistics were performed for the evaluation of interobserver agreement and the McNemar test was performed for the analysis of staging accuracy. When only T1‐ and T2‐weighted images were used, 5 of 32 tumors were not detected and the extent of 18 of 32 tumors were unclear. However, when gadopentetate dimeglumine enhanced fat‐suppressed imaging was added, 24 of 32 tumors were well defined and only one tumor was not detected. In determining the depth of invasion, the staging accuracy was 72% for conventional imaging and 68% for all images combined. There was no significant difference between with gadopentetate dimeglumine fat‐suppressed imaging and conventional imaging (P > .05). Use of gadopentetate dimeglumine (fat‐suppressed imaging) resulted in overestimation of muscular invasion, peri‐rectal fat invasion, and adjacent organ invasion in 12 patients, whereas nine patients were overestimated without the use of gadopentetate dimeglumine. In the detection of metastatic lymph nodes, gadopentetate dimeglumine enhanced fat‐suppressed imaging also was not useful. Tumor detection was excellent using gadopentetate dimeglumine enhanced fat‐suppressed images. However, the accuracy of staging was not improved by obtaining such images.</description><subject>Adipose Tissue - pathology</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biopsy</subject><subject>Colon</subject><subject>Colon, MR studies</subject><subject>Colon, neoplasms</subject><subject>Contrast Media</subject><subject>Drug Combinations</subject><subject>Female</subject><subject>Gadolinium DTPA</subject><subject>Humans</subject><subject>Image Enhancement - instrumentation</subject><subject>Image Processing, Computer-Assisted - instrumentation</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Magnetic Resonance Imaging - instrumentation</subject><subject>Male</subject><subject>Meglumine</subject><subject>Middle Aged</subject><subject>MR studies</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Staging</subject><subject>neoplasms</subject><subject>Organometallic Compounds</subject><subject>Pentetic Acid - analogs & derivatives</subject><subject>Prospective Studies</subject><subject>Rectal Neoplasms - diagnosis</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectum - pathology</subject><subject>Rectum MR studies</subject><subject>Rectum neoplasms</subject><issn>1053-1807</issn><issn>1522-2586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUE1v1DAUtBColMKZE5JP3NL62w6cUAWlaFvQCsTR8tovi0vipHZS2H-Pq10VceL03sybGT0NQi8pOaWEsLObIcdTagwhinDSPkLHVDLWMGnU47oTyRtqiH6KnpVyQwhpWyGP0JHRTAjKjtFuDX52PfYu-5jGwb3BX_JYpsrGO8B-HCaXYxkTHruK0h2kOY6pOlwKeOvCOFUGZjcDDnGAbb8MMQGG9MMlDwF3bm7KMk0ZSqnwao3j4LYxbZ-jJ53rC7w4zBP07cP7r-cfm9Xni8vzd6vGC2HaxjMInknVMsN1UFxQKqX2fFNpLh1IACa8CYFUTKTRivLObNymc7rlSvAT9HqfO-XxdoEy2yEWD33vEoxLsdowoYgwVXi2F_paQMnQ2SnXX_POUmLvy7b3Zdu_ZVfHq0P0shkgPOgP7db72_39V-xh9784--lqfflPerN3xzLD7we3yz-t0lxL-_36wmp2zdmqXVnF_wAsQ54D</recordid><startdate>199605</startdate><enddate>199605</enddate><creator>Okizuka, Hiromi</creator><creator>Sugimura, Kazuro</creator><creator>Yoshizako, Takeshi</creator><creator>Kaji, Yasushi</creator><creator>Wada, Akihiko</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199605</creationdate><title>Rectal carcinoma: Prospective comparison of conventional and gadopentetate dimeglumine enhanced fat-suppressed MR imaging</title><author>Okizuka, Hiromi ; Sugimura, Kazuro ; Yoshizako, Takeshi ; Kaji, Yasushi ; Wada, Akihiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4489-c2edc25692837d63411557c3bedc35ae5ee24c8dd0dc30587613f8babfa793643</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adipose Tissue - pathology</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biopsy</topic><topic>Colon</topic><topic>Colon, MR studies</topic><topic>Colon, neoplasms</topic><topic>Contrast Media</topic><topic>Drug Combinations</topic><topic>Female</topic><topic>Gadolinium DTPA</topic><topic>Humans</topic><topic>Image Enhancement - instrumentation</topic><topic>Image Processing, Computer-Assisted - instrumentation</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis</topic><topic>Magnetic Resonance Imaging - instrumentation</topic><topic>Male</topic><topic>Meglumine</topic><topic>Middle Aged</topic><topic>MR studies</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Staging</topic><topic>neoplasms</topic><topic>Organometallic Compounds</topic><topic>Pentetic Acid - analogs & derivatives</topic><topic>Prospective Studies</topic><topic>Rectal Neoplasms - diagnosis</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectum - pathology</topic><topic>Rectum MR studies</topic><topic>Rectum neoplasms</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okizuka, Hiromi</creatorcontrib><creatorcontrib>Sugimura, Kazuro</creatorcontrib><creatorcontrib>Yoshizako, Takeshi</creatorcontrib><creatorcontrib>Kaji, Yasushi</creatorcontrib><creatorcontrib>Wada, Akihiko</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of magnetic resonance imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okizuka, Hiromi</au><au>Sugimura, Kazuro</au><au>Yoshizako, Takeshi</au><au>Kaji, Yasushi</au><au>Wada, Akihiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rectal carcinoma: Prospective comparison of conventional and gadopentetate dimeglumine enhanced fat-suppressed MR imaging</atitle><jtitle>Journal of magnetic resonance imaging</jtitle><addtitle>J. Magn. Reson. Imaging</addtitle><date>1996-05</date><risdate>1996</risdate><volume>6</volume><issue>3</issue><spage>465</spage><epage>471</epage><pages>465-471</pages><issn>1053-1807</issn><eissn>1522-2586</eissn><abstract>The purpose of this study is to compare the usefulness of conventional MR imaging and gadopentetate dimeglumine enhanced fat‐suppressed MR imaging for the depiction and staging of rectal carcinoma. Thirty‐two patients were prospectively evaluated by MR imaging using a 1.5‐T unit. Based on the results of a barium study and/or digital examination, a balloon catheter was inserted to the level of the lesion before examination. Both conventional T1‐ and T2‐weighted images and gadopentetate dimeglumine enhanced fat‐suppressed T1‐weighted images were obtained for all patients. The kappa statistics were performed for the evaluation of interobserver agreement and the McNemar test was performed for the analysis of staging accuracy. When only T1‐ and T2‐weighted images were used, 5 of 32 tumors were not detected and the extent of 18 of 32 tumors were unclear. However, when gadopentetate dimeglumine enhanced fat‐suppressed imaging was added, 24 of 32 tumors were well defined and only one tumor was not detected. In determining the depth of invasion, the staging accuracy was 72% for conventional imaging and 68% for all images combined. There was no significant difference between with gadopentetate dimeglumine fat‐suppressed imaging and conventional imaging (P > .05). Use of gadopentetate dimeglumine (fat‐suppressed imaging) resulted in overestimation of muscular invasion, peri‐rectal fat invasion, and adjacent organ invasion in 12 patients, whereas nine patients were overestimated without the use of gadopentetate dimeglumine. In the detection of metastatic lymph nodes, gadopentetate dimeglumine enhanced fat‐suppressed imaging also was not useful. Tumor detection was excellent using gadopentetate dimeglumine enhanced fat‐suppressed images. However, the accuracy of staging was not improved by obtaining such images.</abstract><cop>Baltimore</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>8724412</pmid><doi>10.1002/jmri.1880060309</doi><tpages>7</tpages></addata></record> |
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subjects | Adipose Tissue - pathology Aged Aged, 80 and over Biopsy Colon Colon, MR studies Colon, neoplasms Contrast Media Drug Combinations Female Gadolinium DTPA Humans Image Enhancement - instrumentation Image Processing, Computer-Assisted - instrumentation Lymph Nodes - pathology Lymphatic Metastasis Magnetic Resonance Imaging - instrumentation Male Meglumine Middle Aged MR studies Neoplasm Invasiveness Neoplasm Staging neoplasms Organometallic Compounds Pentetic Acid - analogs & derivatives Prospective Studies Rectal Neoplasms - diagnosis Rectal Neoplasms - pathology Rectum - pathology Rectum MR studies Rectum neoplasms |
title | Rectal carcinoma: Prospective comparison of conventional and gadopentetate dimeglumine enhanced fat-suppressed MR imaging |
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