Influence of Genetic Obesity, Food Intake and Adrenalectomy in Mice on Selected Trace Element-Dependent Protective Enzymes

Experiments were conducted to determine if food intake and adrenalectomy influenced abnormal antioxidant defense mechanisms observed in obese mice. Paired male C57BL/6J mice of two genotypes, obese (ob/ob) and lean (+/?), were fed a nonpurified diet ad libitum or restricted (2.5 g/d) until 3 mo old....

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Veröffentlicht in:	The Journal of nutrition 1988-06, Vol.118 (6), p.739-746
Hauptverfasser:	Prohaska, Joseph R., Wittmers, Lorentz E., Haller, Edwin W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - physiology Adrenalectomy Animals Biological and medical sciences Brain - metabolism C57BL/6J ob/ob ceruloplasmin Ceruloplasmin - metabolism copper diabetes Enzymes - metabolism Food Deprivation - physiology food restriction Gene Expression Regulation glutathione peroxidase Glutathione Peroxidase - metabolism glutathione transferase Glutathione Transferase - metabolism iron Kidney - metabolism Liver - metabolism Male Medical sciences Metabolic diseases Mice Mice, Inbred C57BL Mice, Obese obese mice Obesity - enzymology Obesity - genetics Organ Size superoxide dismutase Superoxide Dismutase - metabolism Trace Elements - physiology
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