Human brain S100β and S100β mRNA expression increases with age: Pathogenic implications for Alzheimer's disease

S100β is a neurite extension factor that has been implicated in the development of neuritic plaques in Alzheimer's disease. We analyzed the expression of S100β and its encoding mRNA, using immunohistochemistry, enzyme-linked immunosorbent assay, and Northern blot analysis, in postmortem brain t...

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Veröffentlicht in:	Neurobiology of aging 1996-05, Vol.17 (3), p.359-363
Hauptverfasser:	Sheng, Jin G., Mrak, Robert E., Rovnaghi, Cynthia R., Kozlowska, Ewa, Van Eldik, Linda J., Griffin, W.Sue T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Distribution Aged Aging Aging - metabolism Alzheimer Disease - metabolism Alzheimer's disease Astrocytes - metabolism Biological and medical sciences Brain Brain - metabolism Child Child, Preschool Cytokines - metabolism Development. Senescence. Regeneration. Transplantation ELISA Female Fundamental and applied biological sciences. Psychology Humans Immunohistochemistry Infant Male Middle Aged Northern blot RNA, Messenger - metabolism S100β S100βmRNA Vertebrates: nervous system and sense organs
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