Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin

The small GTP-binding protein Rho rapidly stimulates the formation of focal adhesions and actin stress fibres when microinjected into serum-starved Swiss 3T3 fibroblasts. This response is inhibited by tyrosine kinase inhibitors. Addition of growth factors such as lysophosphatidic acid and bombesin t...

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Veröffentlicht in:	Journal of cell science 1996-05, Vol.109 ( Pt 5) (5), p.1133-1141
Hauptverfasser:	Flinn, H M, Ridley, A J
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Actins - ultrastructure Acute-Phase Proteins - immunology Animals Antigens - immunology Cell Adhesion Molecules - metabolism Crk-Associated Substrate Protein Cytoskeletal Proteins - metabolism Cytoskeleton - ultrastructure Focal Adhesion Kinase 1 Focal Adhesion Protein-Tyrosine Kinases Immunohistochemistry Mice Paxillin Phosphoproteins - metabolism Phosphorylation Protein-Tyrosine Kinases - metabolism Proteins Retinoblastoma-Like Protein p130
Online-Zugang:	Volltext
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