Short increase of BDNF messenger RNA triggers kainic acid-induced neuronal hypertrophy in adult mice

Neurotrophin gene expression in adult brain varies according to physiological activity and following brain injury, suggesting a role in neuronal maintenance and plasticity. However, the exact roles and mechanisms of action of neurotrophins in the adult brain are still poorly understood. We have rece...

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Veröffentlicht in:	Neuroscience 1996-06, Vol.72 (4), p.923-931
Hauptverfasser:	Guilhem, D., Dreyfus, P.A., Makiura, Y., Suzuki, F., Onteniente, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	adult brain Anatomy Animals Biological and medical sciences Brain-Derived Neurotrophic Factor - genetics Carbazoles - pharmacology Central nervous system Dentate Gyrus - pathology Enzyme Inhibitors - pharmacology Excitatory Amino Acid Agonists - pharmacology Fundamental and applied biological sciences. Psychology hippocampus Hypertrophy Indole Alkaloids Injections, Intraventricular Kainic Acid - pharmacology Male Mice Mice, Inbred C57BL mouse Nerve Growth Factors - genetics neuronal plasticity Neuronal Plasticity - drug effects Neurons - drug effects Neurons - pathology neurotrophin Oligonucleotides, Antisense - pharmacology Recombinant Proteins - pharmacology RNA, Messenger - metabolism Vertebrates: nervous system and sense organs
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