Monoclonal IgG as antigens: reduction is an early intracellular event of their processing by antigen-presenting cells
Murine mAb injected into patients behave as exogenous antigens and trigger a specific immune response characterized mainly by CD4+ T lymphocytes. They are recognized by T cells under a processed form and in a MHC class II-restricted fashion. IgG degradation which occurs in antigen-presenting cells (...
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Veröffentlicht in: | International immunology 1996-02, Vol.8 (2), p.211-219 |
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