CBFB/MYH11 Fusion Transcripts in A Case of Acute Myelogenous Leukemia (M1) with Partial Deletion of the Long Arm of Chromosome 16

Pericentric inversion of chromosome 16 [inv(16)(p13q22)] is seen in patients with acute myelomonocytic leukemia with bone marrow eosinophilia. This inversion juxtaposes the MYH11 gene on p13 and the CBFB gene on q22, resulting in the formation of a chimeric mRNA transcript. We describe a patient wit...

Ausführliche Beschreibung