Binding of calcium ions and their effect on clotting of fibrinogen Milano III, a variant with truncated Aα-chains

Calcium ions are known to be required for normal polymerisation of fibrin monomers. Normal human fibrinogen has three high-affinity calcium binding sites. Two of these are located in the D-domains whereas the third binding site was tentatively assigned either to the E-domain or to the C-terminal par...

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Veröffentlicht in:	Blood coagulation & fibrinolysis 1996-04, Vol.7 (3), p.331-335
Hauptverfasser:	Furlan, M, Steinmann, C, Jungo, M, Lämmle, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Coagulation Blood coagulation. Blood cells Calcium - metabolism Coagulation factors Fibrinogens, Abnormal - chemistry Fibrinogens, Abnormal - metabolism Fundamental and applied biological sciences. Psychology Humans Molecular and cellular biology
Online-Zugang:	Volltext
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