The effect of hypoxaemia on drug disposition in chronic respiratory failure

The influence of hypoxaemia on the disposition of two common drugs has been examined in ten adults with stable chronic respiratory failure. There were two experimental periods in this cross-over study: during these periods supplemental oxygen was either withheld or administered to impose clinical hy...

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Veröffentlicht in:	European journal of clinical pharmacology 1996, Vol.50 (1-2), p.77-82
Hauptverfasser:	ROWETT, D, LATIMER, K, SANSOM, L. N, RUFFIN, R. E, MAY, F, HENDERSON, G, HAYBALL, P. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - pharmacokinetics Adult Aged Analgesics, Non-Narcotic - pharmacokinetics Antihypertensive agents Biological and medical sciences Biological Availability Cardiovascular system Chronic Disease Cross-Over Studies Female Furosemide - pharmacokinetics Humans Hypoglycemic Agents - pharmacokinetics Hypoxia - metabolism Male Medical sciences Middle Aged Oxygen Consumption - drug effects Pharmacology. Drug treatments Protein Binding Respiratory Insufficiency - metabolism
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