Porcine islet cells of Langerhans are destroyed by human complement and not by antibody-dependent cell-mediated mechanisms

In the near future, xenotransplantation of porcine islets of Langerhans might be an alternative in the treatment of patients with diabetes mellitus. However, xenotransplantation of islets of Langerhans in large animals has been shown to result in an exceedingly short graft survival, which suggests t...

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