Physical Mapping of the Retinoblastoma Interacting Zinc Finger Gene RIZ to D1S228 on Chromosome 1p36
The retinoblastoma interacting zinc finger gene RIZ is a member of the recently discovered PR domain family that includes the MDS1–EVI1 breakpoint gene involved in human leukemia. To help understand the role of RIZ in human diseases, we have determined the cytogenetic and physical localizations of t...
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Veröffentlicht in: | Genomics 1996-05, Vol.34 (1), p.119-121 |
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creator | Buyse, Inge M. Takahashi, Ei-ichi Huang, Shi |
description | The retinoblastoma interacting zinc finger gene RIZ is a member of the recently discovered PR domain family that includes the MDS1–EVI1 breakpoint gene involved in human leukemia. To help understand the role of RIZ in human diseases, we have determined the cytogenetic and physical localizations of the RIZ gene. Using fluorescencein situhybridization, we determined that RIZ maps to 1p36. On the physical map, RIZ is adjacent to the polymorphic marker D1S228. We suggest that the RIZ gene may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, and lymphoid tumors. |
doi_str_mv | 10.1006/geno.1996.0249 |
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To help understand the role of RIZ in human diseases, we have determined the cytogenetic and physical localizations of the RIZ gene. Using fluorescencein situhybridization, we determined that RIZ maps to 1p36. On the physical map, RIZ is adjacent to the polymorphic marker D1S228. We suggest that the RIZ gene may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, and lymphoid tumors.</description><identifier>ISSN: 0888-7543</identifier><identifier>EISSN: 1089-8646</identifier><identifier>DOI: 10.1006/geno.1996.0249</identifier><identifier>PMID: 8661032</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>AMINO ACIDS ; Base Sequence ; Biological and medical sciences ; BIOLOGICAL MARKERS ; BIOLOGY AND MEDICINE, BASIC STUDIES ; CHROMOSOMAL ABERRATIONS ; Chromosome Mapping ; Chromosomes, Artificial, Yeast ; Chromosomes, Human, Pair 1 ; Classical genetics, quantitative genetics, hybrids ; DNA SEQUENCING ; DNA-Binding Proteins ; DNA-CLONING ; FLUORESCENCE ; Fundamental and applied biological sciences. Psychology ; GENE MUTATIONS ; GENES ; GENETIC MAPPING ; Genetic Markers ; Genetics of eukaryotes. Biological and molecular evolution ; HEREDITARY DISEASES ; Histone-Lysine N-Methyltransferase ; Human ; HUMAN CHROMOSOME 1 ; Humans ; In Situ Hybridization, Fluorescence ; IN-SITU HYBRIDIZATION ; MAN ; Molecular Sequence Data ; NEOPLASMS ; Nuclear Proteins - genetics ; POLYMERASE CHAIN REACTION ; PROTEINS ; STRUCTURE-ACTIVITY RELATIONSHIPS ; Transcription Factors</subject><ispartof>Genomics, 1996-05, Vol.34 (1), p.119-121</ispartof><rights>1996 Academic Press</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491t-b668661b587e0e8d44039eb198a118991e67f0b7a71ef6dea8af2b20bebab7443</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0888754396902499$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3093636$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8661032$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/478567$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Buyse, Inge M.</creatorcontrib><creatorcontrib>Takahashi, Ei-ichi</creatorcontrib><creatorcontrib>Huang, Shi</creatorcontrib><title>Physical Mapping of the Retinoblastoma Interacting Zinc Finger Gene RIZ to D1S228 on Chromosome 1p36</title><title>Genomics</title><addtitle>Genomics</addtitle><description>The retinoblastoma interacting zinc finger gene RIZ is a member of the recently discovered PR domain family that includes the MDS1–EVI1 breakpoint gene involved in human leukemia. To help understand the role of RIZ in human diseases, we have determined the cytogenetic and physical localizations of the RIZ gene. Using fluorescencein situhybridization, we determined that RIZ maps to 1p36. On the physical map, RIZ is adjacent to the polymorphic marker D1S228. We suggest that the RIZ gene may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, and lymphoid tumors.</description><subject>AMINO ACIDS</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>BIOLOGICAL MARKERS</subject><subject>BIOLOGY AND MEDICINE, BASIC STUDIES</subject><subject>CHROMOSOMAL ABERRATIONS</subject><subject>Chromosome Mapping</subject><subject>Chromosomes, Artificial, Yeast</subject><subject>Chromosomes, Human, Pair 1</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>DNA SEQUENCING</subject><subject>DNA-Binding Proteins</subject><subject>DNA-CLONING</subject><subject>FLUORESCENCE</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>GENE MUTATIONS</subject><subject>GENES</subject><subject>GENETIC MAPPING</subject><subject>Genetic Markers</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>HEREDITARY DISEASES</subject><subject>Histone-Lysine N-Methyltransferase</subject><subject>Human</subject><subject>HUMAN CHROMOSOME 1</subject><subject>Humans</subject><subject>In Situ Hybridization, Fluorescence</subject><subject>IN-SITU HYBRIDIZATION</subject><subject>MAN</subject><subject>Molecular Sequence Data</subject><subject>NEOPLASMS</subject><subject>Nuclear Proteins - genetics</subject><subject>POLYMERASE CHAIN REACTION</subject><subject>PROTEINS</subject><subject>STRUCTURE-ACTIVITY RELATIONSHIPS</subject><subject>Transcription Factors</subject><issn>0888-7543</issn><issn>1089-8646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFrFDEUgINY6nb16k2IIN5mTWYymeQoq20XKoqtl15CknnTjcwkY5It9N-bYZfeRHJ4gfe9x3vvQ-gtJRtKCP_0AD5sqJR8Q2omX6AVJUJWgjP-Eq2IEKLqWta8Qhcp_SaEyEbU5-hccE5JU69Q_2P_lJzVI_6m59n5BxwGnPeAf0J2PphRpxwmjXc-Q9Q2L8S98xZflh9EfAW-sLt7nAP-Qm_rWuDg8XYfwxRSmADTueGv0dmgxwRvTnGNfl1-vdteVzffr3bbzzeVZZLmynC-zGVa0QEB0TNGGgmGSqEpFVJS4N1ATKc7CgPvQQs91KYmBow2HWPNGr0_9g0pO5Wsy2D3NngPNivWiZZ3hfl4ZOYY_hwgZTW5ZGEctYdwSKoTVNRt83-QtpzKlssCbo6gjSGlCIOao5t0fFKUqMWRWhypxZFaHJWCd6fOBzNB_4yfpJT8h1Nep2JmiNpbl56xpkjk5a2ROGJQTvroIC4bg7fQu7gs3Af3rwn-AqmSqvc</recordid><startdate>19960515</startdate><enddate>19960515</enddate><creator>Buyse, Inge M.</creator><creator>Takahashi, Ei-ichi</creator><creator>Huang, Shi</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19960515</creationdate><title>Physical Mapping of the Retinoblastoma Interacting Zinc Finger Gene RIZ to D1S228 on Chromosome 1p36</title><author>Buyse, Inge M. ; Takahashi, Ei-ichi ; Huang, Shi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-b668661b587e0e8d44039eb198a118991e67f0b7a71ef6dea8af2b20bebab7443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>AMINO ACIDS</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>BIOLOGICAL MARKERS</topic><topic>BIOLOGY AND MEDICINE, BASIC STUDIES</topic><topic>CHROMOSOMAL ABERRATIONS</topic><topic>Chromosome Mapping</topic><topic>Chromosomes, Artificial, Yeast</topic><topic>Chromosomes, Human, Pair 1</topic><topic>Classical genetics, quantitative genetics, hybrids</topic><topic>DNA SEQUENCING</topic><topic>DNA-Binding Proteins</topic><topic>DNA-CLONING</topic><topic>FLUORESCENCE</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>GENE MUTATIONS</topic><topic>GENES</topic><topic>GENETIC MAPPING</topic><topic>Genetic Markers</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>HEREDITARY DISEASES</topic><topic>Histone-Lysine N-Methyltransferase</topic><topic>Human</topic><topic>HUMAN CHROMOSOME 1</topic><topic>Humans</topic><topic>In Situ Hybridization, Fluorescence</topic><topic>IN-SITU HYBRIDIZATION</topic><topic>MAN</topic><topic>Molecular Sequence Data</topic><topic>NEOPLASMS</topic><topic>Nuclear Proteins - genetics</topic><topic>POLYMERASE CHAIN REACTION</topic><topic>PROTEINS</topic><topic>STRUCTURE-ACTIVITY RELATIONSHIPS</topic><topic>Transcription Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Buyse, Inge M.</creatorcontrib><creatorcontrib>Takahashi, Ei-ichi</creatorcontrib><creatorcontrib>Huang, Shi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Genomics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Buyse, Inge M.</au><au>Takahashi, Ei-ichi</au><au>Huang, Shi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Physical Mapping of the Retinoblastoma Interacting Zinc Finger Gene RIZ to D1S228 on Chromosome 1p36</atitle><jtitle>Genomics</jtitle><addtitle>Genomics</addtitle><date>1996-05-15</date><risdate>1996</risdate><volume>34</volume><issue>1</issue><spage>119</spage><epage>121</epage><pages>119-121</pages><issn>0888-7543</issn><eissn>1089-8646</eissn><abstract>The retinoblastoma interacting zinc finger gene RIZ is a member of the recently discovered PR domain family that includes the MDS1–EVI1 breakpoint gene involved in human leukemia. To help understand the role of RIZ in human diseases, we have determined the cytogenetic and physical localizations of the RIZ gene. Using fluorescencein situhybridization, we determined that RIZ maps to 1p36. On the physical map, RIZ is adjacent to the polymorphic marker D1S228. We suggest that the RIZ gene may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, and lymphoid tumors.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>8661032</pmid><doi>10.1006/geno.1996.0249</doi><tpages>3</tpages></addata></record> |
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subjects | AMINO ACIDS Base Sequence Biological and medical sciences BIOLOGICAL MARKERS BIOLOGY AND MEDICINE, BASIC STUDIES CHROMOSOMAL ABERRATIONS Chromosome Mapping Chromosomes, Artificial, Yeast Chromosomes, Human, Pair 1 Classical genetics, quantitative genetics, hybrids DNA SEQUENCING DNA-Binding Proteins DNA-CLONING FLUORESCENCE Fundamental and applied biological sciences. Psychology GENE MUTATIONS GENES GENETIC MAPPING Genetic Markers Genetics of eukaryotes. Biological and molecular evolution HEREDITARY DISEASES Histone-Lysine N-Methyltransferase Human HUMAN CHROMOSOME 1 Humans In Situ Hybridization, Fluorescence IN-SITU HYBRIDIZATION MAN Molecular Sequence Data NEOPLASMS Nuclear Proteins - genetics POLYMERASE CHAIN REACTION PROTEINS STRUCTURE-ACTIVITY RELATIONSHIPS Transcription Factors |
title | Physical Mapping of the Retinoblastoma Interacting Zinc Finger Gene RIZ to D1S228 on Chromosome 1p36 |
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