A Drosophila Protein-tyrosine Phosphatase Associates with an Adapter Protein Required for Axonal Guidance

We have used the yeast two-hybrid system to isolate a novel Drosophila adapter protein, which interacts with the Drosophila protein-tyrosine phosphatase (PTP) dPTP61F. Absence of this protein in Drosophila causes the mutant photoreceptor axon phenotype dreadlocks (dock) (Garrity, P. A., Rao, Y., Sal...

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Veröffentlicht in:	The Journal of biological chemistry 1996-07, Vol.271 (29), p.17002-17005
Hauptverfasser:	Clemens, James C., Ursuliak, Zenovia, Clemens, Kristina K., Price, James V., Dixon, Jack E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Amino Acid Sequence ANIMAL PROTEINS Animals Axons - physiology BINDING CELLS CELLULE CELULAS Consensus Sequence DROSOPHILA Drosophila melanogaster - genetics Drosophila melanogaster - physiology Drosophila Proteins Embryo, Nonmammalian ESTERASAS ESTERASE ESTERASES FOTORECEPTORES Gene Expression Regulation, Developmental Gene Library Humans Larva Mammals MOLECULAR SEQUENCE DATA NERF Nerve Tissue Proteins - biosynthesis Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - metabolism NERVES NERVIOS Oncogene Proteins - chemistry PHOSPHOPROTEIN PHOSPHATASE PHOTORECEPTEUR Photoreceptor Cells, Invertebrate - physiology PHOTORECEPTORS Polymerase Chain Reaction Protein Tyrosine Phosphatases - metabolism PROTEINAS PROTEINE PROTEINS Recombinant Proteins - biosynthesis Recombinant Proteins - chemistry Recombinant Proteins - metabolism RNA, Messenger - biosynthesis Sequence Homology, Amino Acid src Homology Domains TIROSINA Transcription, Genetic TYROSINE
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