Staging and prognosis of chronic lymphocytic leukemia: the Manitoba experience
Three hundred ninety-one cases of chronic lymphocytic leukemia (CLL) from the Tumour Registry of Manitoba, spanning a 20-year period from January 1960 to December 1979, were reviewed. Survival curves were developed using the staging systems of Rai and Binet. A clear separation in survival was found...
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| Veröffentlicht in: | Journal of general internal medicine : JGIM 1988-03, Vol.3 (2), p.139-143 |
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| container_title | Journal of general internal medicine : JGIM |
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| creator | MacDougall, B K Weinerman, B H |
| description | Three hundred ninety-one cases of chronic lymphocytic leukemia (CLL) from the Tumour Registry of Manitoba, spanning a 20-year period from January 1960 to December 1979, were reviewed. Survival curves were developed using the staging systems of Rai and Binet. A clear separation in survival was found utilizing the system of Binet. Also, there was a significant increase in the development of secondary malignancies (observed, 53; expected, 31, p less than 0.01). However, there was no significant increase in secondary malignancies if only those malignancies occurring at least six months after the diagnosis of chronic lymphocytic leukemia was made were analyzed (observed, 38; expected, 29, p = 0.26). This suggests that the increase in secondary malignancies is not treatment-related, and may be due to the underlying disease. |
| doi_str_mv | 10.1007/BF02596118 |
| format | Article |
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Survival curves were developed using the staging systems of Rai and Binet. A clear separation in survival was found utilizing the system of Binet. Also, there was a significant increase in the development of secondary malignancies (observed, 53; expected, 31, p less than 0.01). However, there was no significant increase in secondary malignancies if only those malignancies occurring at least six months after the diagnosis of chronic lymphocytic leukemia was made were analyzed (observed, 38; expected, 29, p = 0.26). 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| ispartof | Journal of general internal medicine : JGIM, 1988-03, Vol.3 (2), p.139-143 |
| issn | 0884-8734 1525-1497 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Female Humans Leukemia, Lymphoid - mortality Leukemia, Lymphoid - pathology Male Manitoba Neoplasm Staging Prognosis Registries Retrospective Studies |
| title | Staging and prognosis of chronic lymphocytic leukemia: the Manitoba experience |
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