Neutrophil activation by surface bound IgG: Pertussis toxin insensitive activation

Surface bound IgG induces neutrophil degranulation and production of superoxide radicals by a mechanism that is not inhibited by either pertussis toxin or cholera toxin, whereas these functions induced by soluble mediators such as FMLP and soluble aggregates of IgG are profoundly inhibited by pertus...

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Veröffentlicht in:	Biochemical and biophysical research communications 1988-04, Vol.152 (1), p.136-142
Hauptverfasser:	Blackburn, Warren D., Heck, Louis W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Calcium - blood Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunoglobulin G - physiology Lactoferrin - blood Neutrophils - drug effects Neutrophils - immunology Neutrophils - physiology Pertussis Toxin Receptors, Antigen, B-Cell - physiology Virulence Factors, Bordetella - pharmacology
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