The importance of the coal tar bath in the Ingram treatment of psoriasis. Evaluation by evaporimetry and laser Doppler flowmetry
SUMMARY The contribution of the tar component to the efficacy of the Ingram regimen in the treatment of psoriasis was assessed in 11 patients with symmetrical lesions on the upper extremities. One arm was immersed in an oil emulsion bath and the other in a coal tar bath. Whole body ultraviolet irrad...
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| Veröffentlicht in: | British journal of dermatology (1951) 1988-03, Vol.118 (3), p.429-434 |
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| container_title | British journal of dermatology (1951) |
| container_volume | 118 |
| creator | FRÖDIN, T. SKOGH, M. MOLIN, L. |
| description | SUMMARY
The contribution of the tar component to the efficacy of the Ingram regimen in the treatment of psoriasis was assessed in 11 patients with symmetrical lesions on the upper extremities. One arm was immersed in an oil emulsion bath and the other in a coal tar bath. Whole body ultraviolet irradiation followed, and dithranol paste was applied to all lesions. Healing was assessed clinically at weekly intervals, and was found to parallel the normalization of transepidermal water loss (TEWL) as determined by evaporimetry, and the dermal blood flow as evaluated by laser Doppler flowmetry. Results obtained with coal tar baths were not significantly different from those obtained with oil emulsion. We conclude that coal tar bath additive has no advantage over oil emulsion in the Ingram regimen. |
| doi_str_mv | 10.1111/j.1365-2133.1988.tb02439.x |
| format | Article |
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The contribution of the tar component to the efficacy of the Ingram regimen in the treatment of psoriasis was assessed in 11 patients with symmetrical lesions on the upper extremities. One arm was immersed in an oil emulsion bath and the other in a coal tar bath. Whole body ultraviolet irradiation followed, and dithranol paste was applied to all lesions. Healing was assessed clinically at weekly intervals, and was found to parallel the normalization of transepidermal water loss (TEWL) as determined by evaporimetry, and the dermal blood flow as evaluated by laser Doppler flowmetry. Results obtained with coal tar baths were not significantly different from those obtained with oil emulsion. We conclude that coal tar bath additive has no advantage over oil emulsion in the Ingram regimen.</description><identifier>ISSN: 0007-0963</identifier><identifier>EISSN: 1365-2133</identifier><identifier>DOI: 10.1111/j.1365-2133.1988.tb02439.x</identifier><identifier>PMID: 3281703</identifier><identifier>CODEN: BJDEAZ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Anthralin - therapeutic use ; Biological and medical sciences ; Blood Flow Velocity ; Coal Tar - therapeutic use ; Combined Modality Therapy ; Female ; Humans ; Lasers ; Male ; Medical sciences ; Middle Aged ; Mineral Oil - therapeutic use ; Pharmacology. Drug treatments ; Psoriasis - physiopathology ; Psoriasis - therapy ; Regional Blood Flow ; Skin - blood supply ; Skin, nail, hair, dermoskeleton ; Ultraviolet Therapy ; Water Loss, Insensible</subject><ispartof>British journal of dermatology (1951), 1988-03, Vol.118 (3), p.429-434</ispartof><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4369-e14e90557b0240754406fa5f454f60b8314cc719e190fd97e80977b4e4dc0c6f3</citedby><cites>FETCH-LOGICAL-c4369-e14e90557b0240754406fa5f454f60b8314cc719e190fd97e80977b4e4dc0c6f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2133.1988.tb02439.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2133.1988.tb02439.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7824568$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3281703$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FRÖDIN, T.</creatorcontrib><creatorcontrib>SKOGH, M.</creatorcontrib><creatorcontrib>MOLIN, L.</creatorcontrib><title>The importance of the coal tar bath in the Ingram treatment of psoriasis. Evaluation by evaporimetry and laser Doppler flowmetry</title><title>British journal of dermatology (1951)</title><addtitle>Br J Dermatol</addtitle><description>SUMMARY
The contribution of the tar component to the efficacy of the Ingram regimen in the treatment of psoriasis was assessed in 11 patients with symmetrical lesions on the upper extremities. One arm was immersed in an oil emulsion bath and the other in a coal tar bath. Whole body ultraviolet irradiation followed, and dithranol paste was applied to all lesions. Healing was assessed clinically at weekly intervals, and was found to parallel the normalization of transepidermal water loss (TEWL) as determined by evaporimetry, and the dermal blood flow as evaluated by laser Doppler flowmetry. Results obtained with coal tar baths were not significantly different from those obtained with oil emulsion. We conclude that coal tar bath additive has no advantage over oil emulsion in the Ingram regimen.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anthralin - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Blood Flow Velocity</subject><subject>Coal Tar - therapeutic use</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Lasers</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mineral Oil - therapeutic use</subject><subject>Pharmacology. Drug treatments</subject><subject>Psoriasis - physiopathology</subject><subject>Psoriasis - therapy</subject><subject>Regional Blood Flow</subject><subject>Skin - blood supply</subject><subject>Skin, nail, hair, dermoskeleton</subject><subject>Ultraviolet Therapy</subject><subject>Water Loss, Insensible</subject><issn>0007-0963</issn><issn>1365-2133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkE1v1DAQhi0EKkvhJyBZCHFLsGM7jjkg0W7pBxVcFsHNcrwTmsX5wPa2uzd-Ok432ju-jDTvO-94HoTeUJLT9N5vcspKkRWUsZyqqspjTQrOVL57ghZH6SlaEEJkRlTJnqMXIWwIoYwIcoJOWFFRSdgC_V3dAW67cfDR9Bbw0OCYOnYwDkfjcW3iHW77x-Z1_8ubDkcPJnbQx8k8hsG3JrQhxxf3xm1NbIce13sM9yaFth1Ev8emX2NnAni8HMbRpdq44eFRe4meNcYFeDXXU_T988Xq_Cq7_XZ5ff7pNrOclSoDykERIeR0KZGCc1I2RjRc8KYkdcUot1ZSBVSRZq0kVERJWXPga0ts2bBT9O6QO_rhzxZC1F0bLDhnehi2QcuKlmVKS8YPB6P1QwgeGj2mM4zfa0r0hF9v9MRYT4z1hF_P-PUuDb-et2zrDtbH0Zl30t_OugnWuMYn6G042mRVcFFWyfbxYHtoHez_4wP67GbJC5UCskNAGyLsjgHG_9alZFLoH18v9ZX4crNa_jzTjP0DTBqx4g</recordid><startdate>198803</startdate><enddate>198803</enddate><creator>FRÖDIN, T.</creator><creator>SKOGH, M.</creator><creator>MOLIN, L.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198803</creationdate><title>The importance of the coal tar bath in the Ingram treatment of psoriasis. Evaluation by evaporimetry and laser Doppler flowmetry</title><author>FRÖDIN, T. ; SKOGH, M. ; MOLIN, L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4369-e14e90557b0240754406fa5f454f60b8314cc719e190fd97e80977b4e4dc0c6f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anthralin - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Blood Flow Velocity</topic><topic>Coal Tar - therapeutic use</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Lasers</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mineral Oil - therapeutic use</topic><topic>Pharmacology. Drug treatments</topic><topic>Psoriasis - physiopathology</topic><topic>Psoriasis - therapy</topic><topic>Regional Blood Flow</topic><topic>Skin - blood supply</topic><topic>Skin, nail, hair, dermoskeleton</topic><topic>Ultraviolet Therapy</topic><topic>Water Loss, Insensible</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FRÖDIN, T.</creatorcontrib><creatorcontrib>SKOGH, M.</creatorcontrib><creatorcontrib>MOLIN, L.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of dermatology (1951)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FRÖDIN, T.</au><au>SKOGH, M.</au><au>MOLIN, L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The importance of the coal tar bath in the Ingram treatment of psoriasis. Evaluation by evaporimetry and laser Doppler flowmetry</atitle><jtitle>British journal of dermatology (1951)</jtitle><addtitle>Br J Dermatol</addtitle><date>1988-03</date><risdate>1988</risdate><volume>118</volume><issue>3</issue><spage>429</spage><epage>434</epage><pages>429-434</pages><issn>0007-0963</issn><eissn>1365-2133</eissn><coden>BJDEAZ</coden><abstract>SUMMARY
The contribution of the tar component to the efficacy of the Ingram regimen in the treatment of psoriasis was assessed in 11 patients with symmetrical lesions on the upper extremities. One arm was immersed in an oil emulsion bath and the other in a coal tar bath. Whole body ultraviolet irradiation followed, and dithranol paste was applied to all lesions. Healing was assessed clinically at weekly intervals, and was found to parallel the normalization of transepidermal water loss (TEWL) as determined by evaporimetry, and the dermal blood flow as evaluated by laser Doppler flowmetry. Results obtained with coal tar baths were not significantly different from those obtained with oil emulsion. We conclude that coal tar bath additive has no advantage over oil emulsion in the Ingram regimen.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>3281703</pmid><doi>10.1111/j.1365-2133.1988.tb02439.x</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | British journal of dermatology (1951), 1988-03, Vol.118 (3), p.429-434 |
| issn | 0007-0963 1365-2133 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult Aged Anthralin - therapeutic use Biological and medical sciences Blood Flow Velocity Coal Tar - therapeutic use Combined Modality Therapy Female Humans Lasers Male Medical sciences Middle Aged Mineral Oil - therapeutic use Pharmacology. Drug treatments Psoriasis - physiopathology Psoriasis - therapy Regional Blood Flow Skin - blood supply Skin, nail, hair, dermoskeleton Ultraviolet Therapy Water Loss, Insensible |
| title | The importance of the coal tar bath in the Ingram treatment of psoriasis. Evaluation by evaporimetry and laser Doppler flowmetry |
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