Lessons Learned from Animal Models of Osteomyelitis
Because of the marked variability in presentation and management of osteomyelitis in patients, research with animal models that mimic the human disease offers a more controlled approach. Presently available animal models have been used to study pathogenesis, diagnosis, and treatment of osteomyelitis...
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| Veröffentlicht in: | Reviews of infectious diseases 1988-01, Vol.10 (1), p.103-110 |
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| container_title | Reviews of infectious diseases |
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| creator | Norden, C W |
| description | Because of the marked variability in presentation and management of osteomyelitis in patients, research with animal models that mimic the human disease offers a more controlled approach. Presently available animal models have been used to study pathogenesis, diagnosis, and treatment of osteomyelitis. Each model has advantages and disadvantages. Although it seems improbable that an ideal model of osteomyelitis will be achieved in the near future, further efforts to develop new experimental models and innovative research with present models are clearly needed. |
| format | Article |
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Presently available animal models have been used to study pathogenesis, diagnosis, and treatment of osteomyelitis. Each model has advantages and disadvantages. 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Although it seems improbable that an ideal model of osteomyelitis will be achieved in the near future, further efforts to develop new experimental models and innovative research with present models are clearly needed.</description><subject>Animal models</subject><subject>Animals</subject><subject>Anti-Infective Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Antimicrobials</subject><subject>Bacteria</subject><subject>Bones</subject><subject>Chickens</subject><subject>Chronic diseases</subject><subject>Disease models</subject><subject>Disease Models, Animal</subject><subject>Dogs</subject><subject>Guinea Pigs</subject><subject>Infections</subject><subject>Osteomyelitis</subject><subject>Osteomyelitis - diagnosis</subject><subject>Osteomyelitis - drug therapy</subject><subject>Osteomyelitis - etiology</subject><subject>Rabbits</subject><subject>Rats</subject><subject>Review Articles</subject><subject>Staphylococcus</subject><issn>0162-0886</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9jztrwzAUhTW0pGnaf9CCpm4G-V5ZkscQ-gKXLO1s_LgCG9lKfe0h_76BmE5n-D4O59yIrUoNJMo5cyfumXulMrTabMQGwaWQ2q3AgpjjyLKgahqplX6Kg9yP3VAF-RVbCiyjl0eeKQ5nCt3c8YO49VVgelxzJ37eXr8PH0lxfP887IukB7BzYkBDm9WK0Gntva-h0bkByn1bIQFqwBxt1uQabOMpTRFdhgYrq4zxucadeLn2nqb4uxDP5dBxQyFUI8WFS-vSzIGyF_F5FZd6oLY8TZf507lcX17405X3PMfpH2udaXAK_wB201SH</recordid><startdate>19880101</startdate><enddate>19880101</enddate><creator>Norden, C W</creator><general>University of Chicago Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19880101</creationdate><title>Lessons Learned from Animal Models of Osteomyelitis</title><author>Norden, C W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j227t-6242d5b0e3844fffb2c4962e9fda3e234239375c9427cfe113385363a7066f943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Animal models</topic><topic>Animals</topic><topic>Anti-Infective Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Antimicrobials</topic><topic>Bacteria</topic><topic>Bones</topic><topic>Chickens</topic><topic>Chronic diseases</topic><topic>Disease models</topic><topic>Disease Models, Animal</topic><topic>Dogs</topic><topic>Guinea Pigs</topic><topic>Infections</topic><topic>Osteomyelitis</topic><topic>Osteomyelitis - diagnosis</topic><topic>Osteomyelitis - drug therapy</topic><topic>Osteomyelitis - etiology</topic><topic>Rabbits</topic><topic>Rats</topic><topic>Review Articles</topic><topic>Staphylococcus</topic><toplevel>online_resources</toplevel><creatorcontrib>Norden, C W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Reviews of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Norden, C W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lessons Learned from Animal Models of Osteomyelitis</atitle><jtitle>Reviews of infectious diseases</jtitle><addtitle>Rev Infect Dis</addtitle><date>1988-01-01</date><risdate>1988</risdate><volume>10</volume><issue>1</issue><spage>103</spage><epage>110</epage><pages>103-110</pages><issn>0162-0886</issn><abstract>Because of the marked variability in presentation and management of osteomyelitis in patients, research with animal models that mimic the human disease offers a more controlled approach. 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| identifier | ISSN: 0162-0886 |
| ispartof | Reviews of infectious diseases, 1988-01, Vol.10 (1), p.103-110 |
| issn | 0162-0886 |
| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing |
| subjects | Animal models Animals Anti-Infective Agents - therapeutic use Antibiotics Antimicrobials Bacteria Bones Chickens Chronic diseases Disease models Disease Models, Animal Dogs Guinea Pigs Infections Osteomyelitis Osteomyelitis - diagnosis Osteomyelitis - drug therapy Osteomyelitis - etiology Rabbits Rats Review Articles Staphylococcus |
| title | Lessons Learned from Animal Models of Osteomyelitis |
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