Hydroxyethylstarch compared with modified gelatin as volume preload before spinal anaesthesia for Caesarean section
We studied 90 patients undergoing elective Caesarean section under spinal anaesthesia who received lactated Ringer's solution 1000 ml with up to 1000 ml of modified gelatin, lactated Ringer's solution 1000 ml with up to 1000 ml of 6% hydroxyethylstarch or only up to 1000 ml of 6% hydroxyet...
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| Veröffentlicht in: | British journal of anaesthesia : BJA 1996-05, Vol.76 (5), p.731-733 |
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| container_title | British journal of anaesthesia : BJA |
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| creator | Vercauteren, M P Hoffmann, V Coppejans, H C Van Steenberge, A L Adriaensen, H A |
| description | We studied 90 patients undergoing elective Caesarean section under spinal anaesthesia who received lactated Ringer's solution 1000 ml with up to 1000 ml of modified gelatin, lactated Ringer's solution 1000 ml with up to 1000 ml of 6% hydroxyethylstarch or only up to 1000 ml of 6% hydroxyethylstarch. Lumbar puncture was performed as soon as 500 ml of the colloid were infused. The incidence of hypotension, number of patients requiring a vasopressor and doses of ephedrine required to restore arterial pressure were significantly lower in favour of those receiving the crystalloid-hydroxyethylstarch combination. In both groups receiving the 2000 ml preload, packed cell volume (PCV) values decreased by more than 20%, which may be of concern in patients already presenting with mild anaemia. In patients who received the colloid without the crystalloid, PCV values decreased by 14% but the risk of severe hypotension was comparable with the crystalloid-gelatin combination. |
| doi_str_mv | 10.1093/bja/76.5.731 |
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Lumbar puncture was performed as soon as 500 ml of the colloid were infused. The incidence of hypotension, number of patients requiring a vasopressor and doses of ephedrine required to restore arterial pressure were significantly lower in favour of those receiving the crystalloid-hydroxyethylstarch combination. In both groups receiving the 2000 ml preload, packed cell volume (PCV) values decreased by more than 20%, which may be of concern in patients already presenting with mild anaemia. In patients who received the colloid without the crystalloid, PCV values decreased by 14% but the risk of severe hypotension was comparable with the crystalloid-gelatin combination.</description><identifier>ISSN: 0007-0912</identifier><identifier>EISSN: 1471-6771</identifier><identifier>DOI: 10.1093/bja/76.5.731</identifier><identifier>PMID: 8688278</identifier><identifier>CODEN: BJANAD</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Abdominal surgery. Urology. Gynecology. Obstetrics ; Adult ; Anesthesia ; Anesthesia depending on type of surgery ; Anesthesia, Obstetrical ; Anesthesia, Spinal ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Cesarean Section ; Ephedrine - administration & dosage ; Female ; Gelatin ; Hematocrit ; Humans ; Hydroxyethyl Starch Derivatives ; Hypotension - prevention & control ; Intraoperative Complications - prevention & control ; Medical sciences ; Plasma Substitutes ; Pregnancy</subject><ispartof>British journal of anaesthesia : BJA, 1996-05, Vol.76 (5), p.731-733</ispartof><rights>1996</rights><rights>1996 INIST-CNRS</rights><rights>Copyright British Medical Association May 1996</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-f35e2448e93574ad2a9784ee4dd3589c9e5b874183a1e938a615abf7f58b92753</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3064344$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8688278$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vercauteren, M P</creatorcontrib><creatorcontrib>Hoffmann, V</creatorcontrib><creatorcontrib>Coppejans, H C</creatorcontrib><creatorcontrib>Van Steenberge, A L</creatorcontrib><creatorcontrib>Adriaensen, H A</creatorcontrib><title>Hydroxyethylstarch compared with modified gelatin as volume preload before spinal anaesthesia for Caesarean section</title><title>British journal of anaesthesia : BJA</title><addtitle>Br J Anaesth</addtitle><addtitle>Br J Anaesth</addtitle><description>We studied 90 patients undergoing elective Caesarean section under spinal anaesthesia who received lactated Ringer's solution 1000 ml with up to 1000 ml of modified gelatin, lactated Ringer's solution 1000 ml with up to 1000 ml of 6% hydroxyethylstarch or only up to 1000 ml of 6% hydroxyethylstarch. Lumbar puncture was performed as soon as 500 ml of the colloid were infused. The incidence of hypotension, number of patients requiring a vasopressor and doses of ephedrine required to restore arterial pressure were significantly lower in favour of those receiving the crystalloid-hydroxyethylstarch combination. In both groups receiving the 2000 ml preload, packed cell volume (PCV) values decreased by more than 20%, which may be of concern in patients already presenting with mild anaemia. In patients who received the colloid without the crystalloid, PCV values decreased by 14% but the risk of severe hypotension was comparable with the crystalloid-gelatin combination.</description><subject>Abdominal surgery. Urology. Gynecology. Obstetrics</subject><subject>Adult</subject><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia, Obstetrical</subject><subject>Anesthesia, Spinal</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cesarean Section</subject><subject>Ephedrine - administration & dosage</subject><subject>Female</subject><subject>Gelatin</subject><subject>Hematocrit</subject><subject>Humans</subject><subject>Hydroxyethyl Starch Derivatives</subject><subject>Hypotension - prevention & control</subject><subject>Intraoperative Complications - prevention & control</subject><subject>Medical sciences</subject><subject>Plasma Substitutes</subject><subject>Pregnancy</subject><issn>0007-0912</issn><issn>1471-6771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcGL1DAUxoso6-zqzasQRPRiZ5MmaZLjMriusOBFz-E1eXUytE1N2tX5743MsAcRPIWX98v3Xr6vql4xumXU8OvuANeq3cqt4uxJtWFCsbpVij2tNpRSVVPDmufVZc4HSplqjLyoLnSrdaP0psp3R5_iryMu--OQF0huT1wcZ0joyc-w7MkYfehDqb7jAEuYCGTyEId1RDInHCJ40mEfE5I8hwkGAhNgXvaYA5ByT3alLHIwkYxuCXF6UT3rYcj48nxeVd9uP37d3dX3Xz593t3c105Is9Q9l9gIodFwqQT4BozSAlF4z6U2zqDstBJMc2CF0dAyCV2veqk70yjJr6p3J905xR9r2cmOITscBpgwrtkqzSRnrC3gm7_AQ1xT-Uu2zCiltBSsQB9OkEsx54S9nVMYIR0to_ZPELYEYVVrpS1BFPz1WXPtRvSP8Nn50n977kN2MPQJJhfyI8ZpK7gQBXt_wuI6_29geyKxWPoQMNnsAk4OfUjFd-tj-PfD32zXsRU</recordid><startdate>19960501</startdate><enddate>19960501</enddate><creator>Vercauteren, M P</creator><creator>Hoffmann, V</creator><creator>Coppejans, H C</creator><creator>Van Steenberge, A L</creator><creator>Adriaensen, H A</creator><general>Elsevier Ltd</general><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>19960501</creationdate><title>Hydroxyethylstarch compared with modified gelatin as volume preload before spinal anaesthesia for Caesarean section</title><author>Vercauteren, M P ; Hoffmann, V ; Coppejans, H C ; Van Steenberge, A L ; Adriaensen, H A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-f35e2448e93574ad2a9784ee4dd3589c9e5b874183a1e938a615abf7f58b92753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Abdominal surgery. Urology. Gynecology. Obstetrics</topic><topic>Adult</topic><topic>Anesthesia</topic><topic>Anesthesia depending on type of surgery</topic><topic>Anesthesia, Obstetrical</topic><topic>Anesthesia, Spinal</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cesarean Section</topic><topic>Ephedrine - administration & dosage</topic><topic>Female</topic><topic>Gelatin</topic><topic>Hematocrit</topic><topic>Humans</topic><topic>Hydroxyethyl Starch Derivatives</topic><topic>Hypotension - prevention & control</topic><topic>Intraoperative Complications - prevention & control</topic><topic>Medical sciences</topic><topic>Plasma Substitutes</topic><topic>Pregnancy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vercauteren, M P</creatorcontrib><creatorcontrib>Hoffmann, V</creatorcontrib><creatorcontrib>Coppejans, H C</creatorcontrib><creatorcontrib>Van Steenberge, A L</creatorcontrib><creatorcontrib>Adriaensen, H A</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of anaesthesia : BJA</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vercauteren, M P</au><au>Hoffmann, V</au><au>Coppejans, H C</au><au>Van Steenberge, A L</au><au>Adriaensen, H A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hydroxyethylstarch compared with modified gelatin as volume preload before spinal anaesthesia for Caesarean section</atitle><jtitle>British journal of anaesthesia : BJA</jtitle><stitle>Br J Anaesth</stitle><addtitle>Br J Anaesth</addtitle><date>1996-05-01</date><risdate>1996</risdate><volume>76</volume><issue>5</issue><spage>731</spage><epage>733</epage><pages>731-733</pages><issn>0007-0912</issn><eissn>1471-6771</eissn><coden>BJANAD</coden><abstract>We studied 90 patients undergoing elective Caesarean section under spinal anaesthesia who received lactated Ringer's solution 1000 ml with up to 1000 ml of modified gelatin, lactated Ringer's solution 1000 ml with up to 1000 ml of 6% hydroxyethylstarch or only up to 1000 ml of 6% hydroxyethylstarch. Lumbar puncture was performed as soon as 500 ml of the colloid were infused. The incidence of hypotension, number of patients requiring a vasopressor and doses of ephedrine required to restore arterial pressure were significantly lower in favour of those receiving the crystalloid-hydroxyethylstarch combination. In both groups receiving the 2000 ml preload, packed cell volume (PCV) values decreased by more than 20%, which may be of concern in patients already presenting with mild anaemia. In patients who received the colloid without the crystalloid, PCV values decreased by 14% but the risk of severe hypotension was comparable with the crystalloid-gelatin combination.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>8688278</pmid><doi>10.1093/bja/76.5.731</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Abdominal surgery. Urology. Gynecology. Obstetrics Adult Anesthesia Anesthesia depending on type of surgery Anesthesia, Obstetrical Anesthesia, Spinal Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cesarean Section Ephedrine - administration & dosage Female Gelatin Hematocrit Humans Hydroxyethyl Starch Derivatives Hypotension - prevention & control Intraoperative Complications - prevention & control Medical sciences Plasma Substitutes Pregnancy |
| title | Hydroxyethylstarch compared with modified gelatin as volume preload before spinal anaesthesia for Caesarean section |
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