The acid metabolite of ZD7114 is a partial agonist of lipolysis mediated by the rat beta 3-adrenoceptor

Experiments were performed to characterise the lipolytic effects of the acid metabolite, ZM215001, ((S)-4-[2-hydroxy-3-phenoxy-propylamino-ethoxy] phenoxyacetic acid) of the putative beta 3-adrenoceptor agonist, ZD7114 ((S)-4-[2-hydroxy-3-phenoxy-propylamino-ethoxy]-N-(2-methoxyethyl) phenoxyacetami...

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Veröffentlicht in:	European journal of pharmacology 1996-01, Vol.295 (2-3), p.199-205
Hauptverfasser:	Mayers, R M, Quayle, S P, Thompson, A J, Grant, T L, Holloway, B R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - drug effects Adrenergic beta-Agonists - pharmacology Animals Dose-Response Relationship, Drug Ethanolamines - pharmacology Isoproterenol - pharmacology Lipolysis - drug effects Male Phenoxyacetates - metabolism Phenoxyacetates - pharmacology Phenoxypropanolamines Rats Rats, Wistar
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