Purification of a Cell-surface Receptor for Surfactant Protein A

In the present report we have characterized the binding of surfactant protein A (SP-A) to bone marrow-derived macrophages, U937 cells, alveolar macrophages, and type II epithelial cells. The binding of SP-A to all cell types is Ca2+-dependent and trypsin-sensitive, but type II cells express distinct...

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Veröffentlicht in:	The Journal of biological chemistry 1996-07, Vol.271 (27), p.16375-16383
Hauptverfasser:	Chroneos, Zissis C., Abdolrasulnia, Rasul, Whitsett, Jeffrey A., Rice, W.R., Shepherd, Virginia L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells Cell Line Cell Membrane - metabolism Chromatography, Affinity Electrophoresis, Polyacrylamide Gel Epithelium - metabolism Humans Kinetics Lung - metabolism Macrophages - metabolism Macrophages, Alveolar - metabolism Male Molecular Weight Phospholipids - metabolism Proteolipids - isolation & purification Proteolipids - metabolism Pulmonary Surfactant-Associated Protein A Pulmonary Surfactant-Associated Proteins Pulmonary Surfactants - isolation & purification Pulmonary Surfactants - metabolism Rats Rats, Sprague-Dawley Receptors, Cell Surface - isolation & purification Receptors, Cell Surface - metabolism Receptors, Cell Surface - physiology
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