EBV latent membrane protein (LMP-1) and bcl-2 protein expression in Reed-Sternberg-like cells in post-transplant lymphoproliferative disorders

An inconsistent association exists between EBV‐LMP‐1 and bcl‐2 protein expression in Reed‐Sternberg cells seen in Hodgkin’s disease. In fact, many studies have concluded that there is no correlation between EBV‐LMP and bcl‐2 expression in Hodgkin's disease. We undertook an analysis of post‐tran...

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Veröffentlicht in:	Histopathology 1996-03, Vol.28 (3), p.257-260
Hauptverfasser:	CHETTY, R., BIDDOLPH, S.C., KAKLAMANIS, L., CARY, N., STEWART, S., GIATROMANOLAKI, A., GATTER, K.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	bcl-2 Biological and medical sciences EBV-LMP-1 Hematologic and hematopoietic diseases Herpesvirus 4, Human - metabolism Humans Immunohistochemistry Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoproliferative Disorders - etiology Lymphoproliferative Disorders - metabolism Lymphoproliferative Disorders - pathology Medical sciences Organ Transplantation - adverse effects post-transplant lymphoproliferative disorders Proto-Oncogene Proteins c-bcl-2 - biosynthesis Reed-Sternberg Cells - metabolism Reed-Sternberg Cells - pathology Reed-Sternberg-like cells Viral Matrix Proteins - biosynthesis
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