Aerosolized recombinant human DNase in hospitalized cystic fibrosis patients with acute pulmonary exacerbations

The goal of this study was to evaluate the safety and efficacy of recombinant human DNase (rhDNase) in hospitalized patients with cystic fibrosis (CF) experiencing acute pulmonary exacerbations. Eighty patients with documented CF were enrolled at 11 CF centers when admitted for antibiotic therapy. P...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1996-06, Vol.153 (6), p.1914-1917
Hauptverfasser:	WILMOTT, R. W, AMIN, R. S, MOSS, R, NASH, M. L, JUE, C. P, REGELMANN, W, STOKES, D. C, FUCHS, H. J, COLIN, A. A, DEVAULT, A, DOZOR, A. J, EIGEN, H, JOHNSON, C, LESTER, L. A, MCCOY, K, MCKEAN, L. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Aerosols Biological and medical sciences Cystic Fibrosis - drug therapy Cystic Fibrosis - physiopathology Deoxyribonuclease I - administration & dosage Deoxyribonuclease I - therapeutic use Double-Blind Method Drug Therapy, Combination Expectorants - administration & dosage Expectorants - therapeutic use Female Hospitalization Humans Male Medical sciences Oxygen - blood Pharmacology. Drug treatments Recombinant Proteins - administration & dosage Recombinant Proteins - therapeutic use Respiratory Function Tests Respiratory system Treatment Outcome
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