Purinergic and adrenergic transmission and their presynaptic modulation in canine isolated perfused splenic arteries

Vasoconstrictions induced by periarterial electrical stimulation were analysed pharmacologically in the canine isolated perfused splenic artery. Phentolamine enhanced the vasoconstrictions at 1 Hz but inhibited those at 10 Hz. Suramin and P 2x purinoceptor desensitization with α,β-methylene ATP abol...

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Veröffentlicht in:	European journal of pharmacology 1996-01, Vol.295 (1), p.61-68
Hauptverfasser:	Ren, Lei-Ming, Nakane, Tokio, Chiba, Shigetoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals Autoinhibition Biological and medical sciences Blood vessels and receptors Dog Dogs Dose-Response Relationship, Drug Electric Stimulation Electrical stimulation Female Fundamental and applied biological sciences. Psychology Male Norepinephrine - pharmacology P 2x purinoceptor Perfusion Prazosin - pharmacology Presynaptic Terminals - drug effects Purinergic transmission Splenic artery Splenic Artery - drug effects Vertebrates: cardiovascular system α2-Adrenoceptor
Online-Zugang:	Volltext
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