A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

THE 5'-exonucleases are enzymes that are essential for DNA replication and repair. As well as their exonucleolytic action, removing nucleotides from the 5'-end of nucleic acid molecules such as Okazaki fragments, many 5'-3'-exonucleases have been shown to possess endonucleolytic...

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Veröffentlicht in:	Nature (London) 1996-07, Vol.382 (6586), p.90-93
Hauptverfasser:	Ceska, T. A, Sayers, J. R, Stier, G, Suck, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Binding Sites Biological and medical sciences Crystallography, X-Ray Deoxyribonucleic acid DNA DNA, Single-Stranded - metabolism Electrochemistry Enzymes Enzymes and enzyme inhibitors Exodeoxyribonucleases - chemistry Exodeoxyribonucleases - metabolism Fundamental and applied biological sciences. Psychology Genetics Hydrolases Models, Molecular phage T5 Protein Conformation Structure-Activity Relationship Surface Properties T-Phages - enzymology
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