Mycobacterium chelonae infection following a total knee arthroplasty

Infection following total knee arthroplasty is a major cause of implant failure, with an incidence of infections between 1 and 12%. Although there have been no previously reported cases of infection with Mycobacterium chelonae following total knee arthroplasty, this mycobacterium appears to be a pot...

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Veröffentlicht in:The Journal of arthroplasty 1996, Vol.11 (1), p.115-116
Hauptverfasser: Pring, Maya, Eckhoff, Donald G.
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container_title The Journal of arthroplasty
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creator Pring, Maya
Eckhoff, Donald G.
description Infection following total knee arthroplasty is a major cause of implant failure, with an incidence of infections between 1 and 12%. Although there have been no previously reported cases of infection with Mycobacterium chelonae following total knee arthroplasty, this mycobacterium appears to be a potential pathogen in arthroplasty. When infection following total knee arthroplasty is evident but standard cultures come back negative, atypical mycobacterium infection should be considered. Mycobacterium chelonae does not grow in the normally allotted culture time, so false negative results are common. Once identified, M. chelonae is difficult to treat because of its resistance to standard drug therapies. Details of the first reported successful diagnosis and treatment of an infection with M. chelonae following a total knee arthroplasty are reported.
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Although there have been no previously reported cases of infection with Mycobacterium chelonae following total knee arthroplasty, this mycobacterium appears to be a potential pathogen in arthroplasty. When infection following total knee arthroplasty is evident but standard cultures come back negative, atypical mycobacterium infection should be considered. Mycobacterium chelonae does not grow in the normally allotted culture time, so false negative results are common. Once identified, M. chelonae is difficult to treat because of its resistance to standard drug therapies. 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subjects Aged
Amikacin - therapeutic use
Cefoxitin - therapeutic use
Drug Therapy, Combination - therapeutic use
False Negative Reactions
Female
Humans
infection
Knee Prosthesis - adverse effects
Mycobacterium chelonae
Mycobacterium chelonae - isolation & purification
Mycobacterium Infections, Nontuberculous - drug therapy
Mycobacterium Infections, Nontuberculous - microbiology
Prosthesis-Related Infections - drug therapy
Prosthesis-Related Infections - microbiology
total knee arthroplasty
Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
title Mycobacterium chelonae infection following a total knee arthroplasty
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