The nuclear Kluyveromyces lactis MRF1 gene encodes a mitochondrial class I peptide chain release factor that is important for cell viability

We report the isolation and characterization of the Kluyveromyces lactis MRF1 gene encoding mitochondrial peptide chain release factor mRF-1. Over-expression of the KlMRF1 gene has a strong antisuppressive effect in a Saccharomyces cerevisiae mitochondrial nonsense suppressor strain. Inactivation of...

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Veröffentlicht in:	Current genetics 1996-06, Vol.30 (1), p.19-28
Hauptverfasser:	Pel, H J, Rozenfeld, S, Bolotin-Fukuhara, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Cell Nucleus - metabolism Chromosome Mapping Cloning, Molecular Fungal Proteins - genetics Fungal Proteins - metabolism Genes, Bacterial Genes, Fungal Kluyveromyces - cytology Kluyveromyces - genetics Kluyveromyces - metabolism Kluyveromyces lactis Listeria monocytogenes - genetics Mitochondria - metabolism Mitochondrial Proteins Molecular Sequence Data Peptide Termination Factors - genetics Peptide Termination Factors - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins Sequence Homology, Amino Acid Transcription Factors
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