6-Hydroxydopamine induces thymocyte apoptosis in mice

6-Hydroxydopamine (6-OHDA) induces degeneration of noradrenergic nerves and has been shown to alter the immune responses. In this study, intraperitoneal administration of 6-OHDA induces mouse thymus atrophy. The lowest levels of thymus weight and cell number were reached at days 3 and 5 in mice rece...

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Veröffentlicht in:	Journal of neuroimmunology 1996-04, Vol.65 (2), p.91-95
Hauptverfasser:	Tsao, Chiung-Wen, Cheng, Juei-Tang, Shen, Ching-Liang, Lin, Yee-Shin
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Hydroxydopamine Animals Apoptosis Desipramine Desipramine - pharmacology DNA Damage - drug effects Mice Mice, Inbred BALB C Organ Size - drug effects Oxidopamine - antagonists & inhibitors Oxidopamine - pharmacology Thymocyte apoptosis Thymus Gland - anatomy & histology Thymus Gland - cytology Thymus Gland - drug effects
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