Mouse RSS spacer sequences affect the rate of V(D)J recombination

The diversity of antigen-specific receptors [immunoglobulins (Ig) and T-cell receptors (Tcr)] is generated largely during the assembly of the genetic elements - named V, D, and J - that encode the variable region of both Ig and Tcr. This assembly involves a somatic, cell-type specific, site-specific...

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Veröffentlicht in:	Immunogenetics (New York) 1996, Vol.44 (2), p.146-150
Hauptverfasser:	Fanning, L, Connor, A, Baetz, K, Ramsden, D, Wu, G E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Immunoglobulin Joining Region - genetics Immunoglobulin kappa-Chains - genetics Immunoglobulin Variable Region - genetics Mice Molecular Sequence Data Recombination, Genetic
Online-Zugang:	Volltext
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