Disability in geriatric depression
OBJECTIVE: The authors' purpose was to identify the relationship of disability to clinical measures that are part of a comprehensive psychiatric examination of depressed elderly patients. METHOD: The disability of 75 elderly inpatients and outpatients with major depression whose cognitive funct...
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Veröffentlicht in: | The American journal of psychiatry 1996-07, Vol.153 (7), p.877-885 |
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container_title | The American journal of psychiatry |
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creator | ALEXOPOULOS, G. S VRONTOU, C KAKUMA, T MEYERS, B. S YOUNG, R. C KLAUSNER, E CLARKIN, J |
description | OBJECTIVE: The authors' purpose was to identify the relationship of
disability to clinical measures that are part of a comprehensive
psychiatric examination of depressed elderly patients. METHOD: The
disability of 75 elderly inpatients and outpatients with major depression
whose cognitive function ranged from normality to mild dementia was
assessed with the Philadelphia Multilevel Assessment Instrument. Age at
onset of depression, chronicity of depression, severity of depression,
cognitive impairment, medical burden, social support and living environment
were assessed with standardized instruments. RESULTS: Impairment in
instrumental activities of daily living was significantly associated with
advanced age, severity of depression, and medical burden. The relationship
of depressive symptoms to impairment in instrumental activities of daily
living was not influenced by age or medical burden. Anxiety and depressive
ideation as well as retardation and weight loss were significantly
associated with impairment in instrumental activities of daily living.
Interviewer- rated global disability was associated with advanced age at
onset of depression, medical burden, and overall cognitive impairment.
Specifically, a disturbance in initiation and perseveration was
significantly related to global disability. CONCLUSIONS: Impairment in
instrumental activities of daily living appears to be a relatively
independent dimension of health status that is related to depressive
symptoms, particularly anxiety and depressive ideation as well as
retardation and weight loss. Global disability may be associated with
impairment in initiation and perseveration and with late onset of
depression. These findings provide a basis for studies investigating
whether psychotherapy aimed at depressive ideation and rehabilitation
efforts focused on instrumental activities of daily living can improve the
outcome of geriatric depression. |
doi_str_mv | 10.1176/ajp.153.7.877 |
format | Article |
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disability to clinical measures that are part of a comprehensive
psychiatric examination of depressed elderly patients. METHOD: The
disability of 75 elderly inpatients and outpatients with major depression
whose cognitive function ranged from normality to mild dementia was
assessed with the Philadelphia Multilevel Assessment Instrument. Age at
onset of depression, chronicity of depression, severity of depression,
cognitive impairment, medical burden, social support and living environment
were assessed with standardized instruments. RESULTS: Impairment in
instrumental activities of daily living was significantly associated with
advanced age, severity of depression, and medical burden. The relationship
of depressive symptoms to impairment in instrumental activities of daily
living was not influenced by age or medical burden. Anxiety and depressive
ideation as well as retardation and weight loss were significantly
associated with impairment in instrumental activities of daily living.
Interviewer- rated global disability was associated with advanced age at
onset of depression, medical burden, and overall cognitive impairment.
Specifically, a disturbance in initiation and perseveration was
significantly related to global disability. CONCLUSIONS: Impairment in
instrumental activities of daily living appears to be a relatively
independent dimension of health status that is related to depressive
symptoms, particularly anxiety and depressive ideation as well as
retardation and weight loss. Global disability may be associated with
impairment in initiation and perseveration and with late onset of
depression. These findings provide a basis for studies investigating
whether psychotherapy aimed at depressive ideation and rehabilitation
efforts focused on instrumental activities of daily living can improve the
outcome of geriatric depression.</description><identifier>ISSN: 0002-953X</identifier><identifier>EISSN: 1535-7228</identifier><identifier>DOI: 10.1176/ajp.153.7.877</identifier><identifier>PMID: 8659609</identifier><identifier>CODEN: AJPSAO</identifier><language>eng</language><publisher>Washington, DC: American Psychiatric Publishing</publisher><subject>Activities of Daily Living ; Age of Onset ; Aged ; Anxiety - psychology ; Biological and medical sciences ; Cognition Disorders - diagnosis ; Cognition Disorders - epidemiology ; Comorbidity ; Dementia - diagnosis ; Dementia - epidemiology ; Depression ; Depression - psychology ; Depressive Disorder - diagnosis ; Depressive Disorder - epidemiology ; Depressive Disorder - rehabilitation ; Disability ; Disability Evaluation ; Elderly people ; Female ; Geriatric Assessment - statistics & numerical data ; Geriatric psychology ; Geriatrics ; Health Status Indicators ; Humans ; Male ; Medical sciences ; Mental depression ; Older people ; Psychiatric Status Rating Scales ; Psychiatry ; Psychology. Psychoanalysis. Psychiatry ; Psychomotor Performance ; Psychopathology. Psychiatry ; Regression Analysis ; Severity of Illness Index ; Social Support ; Weight Loss</subject><ispartof>The American journal of psychiatry, 1996-07, Vol.153 (7), p.877-885</ispartof><rights>1997 INIST-CNRS</rights><rights>Copyright American Psychiatric Association Jul 1996</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a438t-20264cb35a6dc831dcbc42ce0fd7392e0e8776ff4c788c9e1438817a41652b443</citedby><cites>FETCH-LOGICAL-a438t-20264cb35a6dc831dcbc42ce0fd7392e0e8776ff4c788c9e1438817a41652b443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://psychiatryonline.org/doi/epdf/10.1176/ajp.153.7.877$$EPDF$$P50$$Gappi$$H</linktopdf><linktohtml>$$Uhttps://psychiatryonline.org/doi/full/10.1176/ajp.153.7.877$$EHTML$$P50$$Gappi$$H</linktohtml><link.rule.ids>315,781,785,2860,21634,27874,27929,27930,31005,77796,77797</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2749386$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8659609$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ALEXOPOULOS, G. S</creatorcontrib><creatorcontrib>VRONTOU, C</creatorcontrib><creatorcontrib>KAKUMA, T</creatorcontrib><creatorcontrib>MEYERS, B. S</creatorcontrib><creatorcontrib>YOUNG, R. C</creatorcontrib><creatorcontrib>KLAUSNER, E</creatorcontrib><creatorcontrib>CLARKIN, J</creatorcontrib><title>Disability in geriatric depression</title><title>The American journal of psychiatry</title><addtitle>Am J Psychiatry</addtitle><description>OBJECTIVE: The authors' purpose was to identify the relationship of
disability to clinical measures that are part of a comprehensive
psychiatric examination of depressed elderly patients. METHOD: The
disability of 75 elderly inpatients and outpatients with major depression
whose cognitive function ranged from normality to mild dementia was
assessed with the Philadelphia Multilevel Assessment Instrument. Age at
onset of depression, chronicity of depression, severity of depression,
cognitive impairment, medical burden, social support and living environment
were assessed with standardized instruments. RESULTS: Impairment in
instrumental activities of daily living was significantly associated with
advanced age, severity of depression, and medical burden. The relationship
of depressive symptoms to impairment in instrumental activities of daily
living was not influenced by age or medical burden. Anxiety and depressive
ideation as well as retardation and weight loss were significantly
associated with impairment in instrumental activities of daily living.
Interviewer- rated global disability was associated with advanced age at
onset of depression, medical burden, and overall cognitive impairment.
Specifically, a disturbance in initiation and perseveration was
significantly related to global disability. CONCLUSIONS: Impairment in
instrumental activities of daily living appears to be a relatively
independent dimension of health status that is related to depressive
symptoms, particularly anxiety and depressive ideation as well as
retardation and weight loss. Global disability may be associated with
impairment in initiation and perseveration and with late onset of
depression. These findings provide a basis for studies investigating
whether psychotherapy aimed at depressive ideation and rehabilitation
efforts focused on instrumental activities of daily living can improve the
outcome of geriatric depression.</description><subject>Activities of Daily Living</subject><subject>Age of Onset</subject><subject>Aged</subject><subject>Anxiety - psychology</subject><subject>Biological and medical sciences</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - epidemiology</subject><subject>Comorbidity</subject><subject>Dementia - diagnosis</subject><subject>Dementia - epidemiology</subject><subject>Depression</subject><subject>Depression - psychology</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - epidemiology</subject><subject>Depressive Disorder - rehabilitation</subject><subject>Disability</subject><subject>Disability Evaluation</subject><subject>Elderly people</subject><subject>Female</subject><subject>Geriatric Assessment - statistics & numerical data</subject><subject>Geriatric psychology</subject><subject>Geriatrics</subject><subject>Health Status Indicators</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental depression</subject><subject>Older people</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychomotor Performance</subject><subject>Psychopathology. Psychiatry</subject><subject>Regression Analysis</subject><subject>Severity of Illness Index</subject><subject>Social Support</subject><subject>Weight Loss</subject><issn>0002-953X</issn><issn>1535-7228</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><sourceid>7QJ</sourceid><recordid>eNqFkU1LxDAQhoMo67p69CgsKh6E1kzSfPQo6ycseFHwFtI0lSzdtibtYf-9WXZZRBRPmTDPvDPvDEKngFMAwW_0okuB0VSkUog9NI4xSwQhch-NMcYkyRl9P0RHISziF1NBRmgkOcs5zsfo_M4FXbja9aupa6Yf1jvde2empe28DcG1zTE6qHQd7Mn2naC3h_vX2VMyf3l8nt3OE51R2ScEE56ZgjLNSyMplKYwGTEWV6WgObHYxvl4VWVGSGlyC7FKgtAZcEaKLKMTdLXR7Xz7OdjQq6ULxta1bmw7BCUkABDxP8gEF0AYRPD8B7hoB99EE4oQnHGe87XaxV8QMJCUYkZxpJINZXwbgreV6rxbar9SgNX6DireIRZQJVT0GfmzrepQLG25o7eLj_nLbV4Ho-vK68a4sMOizZxKHrHrDaa7zn0b7NeeXwrimiM</recordid><startdate>19960701</startdate><enddate>19960701</enddate><creator>ALEXOPOULOS, G. S</creator><creator>VRONTOU, C</creator><creator>KAKUMA, T</creator><creator>MEYERS, B. S</creator><creator>YOUNG, R. C</creator><creator>KLAUSNER, E</creator><creator>CLARKIN, J</creator><general>American Psychiatric Publishing</general><general>American Psychiatric Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HAWNG</scope><scope>HBMBR</scope><scope>IBDFT</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7QJ</scope><scope>7X8</scope></search><sort><creationdate>19960701</creationdate><title>Disability in geriatric depression</title><author>ALEXOPOULOS, G. S ; VRONTOU, C ; KAKUMA, T ; MEYERS, B. S ; YOUNG, R. C ; KLAUSNER, E ; CLARKIN, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a438t-20264cb35a6dc831dcbc42ce0fd7392e0e8776ff4c788c9e1438817a41652b443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Activities of Daily Living</topic><topic>Age of Onset</topic><topic>Aged</topic><topic>Anxiety - psychology</topic><topic>Biological and medical sciences</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognition Disorders - epidemiology</topic><topic>Comorbidity</topic><topic>Dementia - diagnosis</topic><topic>Dementia - epidemiology</topic><topic>Depression</topic><topic>Depression - psychology</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - epidemiology</topic><topic>Depressive Disorder - rehabilitation</topic><topic>Disability</topic><topic>Disability Evaluation</topic><topic>Elderly people</topic><topic>Female</topic><topic>Geriatric Assessment - statistics & numerical data</topic><topic>Geriatric psychology</topic><topic>Geriatrics</topic><topic>Health Status Indicators</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental depression</topic><topic>Older people</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychomotor Performance</topic><topic>Psychopathology. Psychiatry</topic><topic>Regression Analysis</topic><topic>Severity of Illness Index</topic><topic>Social Support</topic><topic>Weight Loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ALEXOPOULOS, G. S</creatorcontrib><creatorcontrib>VRONTOU, C</creatorcontrib><creatorcontrib>KAKUMA, T</creatorcontrib><creatorcontrib>MEYERS, B. S</creatorcontrib><creatorcontrib>YOUNG, R. C</creatorcontrib><creatorcontrib>KLAUSNER, E</creatorcontrib><creatorcontrib>CLARKIN, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Periodicals Index Online Segment 13</collection><collection>Periodicals Index Online Segment 14</collection><collection>Periodicals Index Online Segment 27</collection><collection>Periodicals Index Online</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - West</collection><collection>Primary Sources Access (Plan D) - International</collection><collection>Primary Sources Access & Build (Plan A) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Midwest</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Northeast</collection><collection>Primary Sources Access (Plan D) - Southeast</collection><collection>Primary Sources Access (Plan D) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Southeast</collection><collection>Primary Sources Access (Plan D) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - UK / I</collection><collection>Primary Sources Access (Plan D) - Canada</collection><collection>Primary Sources Access (Plan D) - EMEALA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - International</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - International</collection><collection>Primary Sources Access (Plan D) - West</collection><collection>Periodicals Index Online Segments 1-50</collection><collection>Primary Sources Access (Plan D) - APAC</collection><collection>Primary Sources Access (Plan D) - Midwest</collection><collection>Primary Sources Access (Plan D) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Canada</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - EMEALA</collection><collection>Primary Sources Access & Build (Plan A) - APAC</collection><collection>Primary Sources Access & Build (Plan A) - Canada</collection><collection>Primary Sources Access & Build (Plan A) - West</collection><collection>Primary Sources Access & Build (Plan A) - EMEALA</collection><collection>Primary Sources Access (Plan D) - Northeast</collection><collection>Primary Sources Access & Build (Plan A) - Midwest</collection><collection>Primary Sources Access & Build (Plan A) - North Central</collection><collection>Primary Sources Access & Build (Plan A) - Northeast</collection><collection>Primary Sources Access & Build (Plan A) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - Southeast</collection><collection>Primary Sources Access (Plan D) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - APAC</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - MEA</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ALEXOPOULOS, G. S</au><au>VRONTOU, C</au><au>KAKUMA, T</au><au>MEYERS, B. S</au><au>YOUNG, R. C</au><au>KLAUSNER, E</au><au>CLARKIN, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disability in geriatric depression</atitle><jtitle>The American journal of psychiatry</jtitle><addtitle>Am J Psychiatry</addtitle><date>1996-07-01</date><risdate>1996</risdate><volume>153</volume><issue>7</issue><spage>877</spage><epage>885</epage><pages>877-885</pages><issn>0002-953X</issn><eissn>1535-7228</eissn><coden>AJPSAO</coden><abstract>OBJECTIVE: The authors' purpose was to identify the relationship of
disability to clinical measures that are part of a comprehensive
psychiatric examination of depressed elderly patients. METHOD: The
disability of 75 elderly inpatients and outpatients with major depression
whose cognitive function ranged from normality to mild dementia was
assessed with the Philadelphia Multilevel Assessment Instrument. Age at
onset of depression, chronicity of depression, severity of depression,
cognitive impairment, medical burden, social support and living environment
were assessed with standardized instruments. RESULTS: Impairment in
instrumental activities of daily living was significantly associated with
advanced age, severity of depression, and medical burden. The relationship
of depressive symptoms to impairment in instrumental activities of daily
living was not influenced by age or medical burden. Anxiety and depressive
ideation as well as retardation and weight loss were significantly
associated with impairment in instrumental activities of daily living.
Interviewer- rated global disability was associated with advanced age at
onset of depression, medical burden, and overall cognitive impairment.
Specifically, a disturbance in initiation and perseveration was
significantly related to global disability. CONCLUSIONS: Impairment in
instrumental activities of daily living appears to be a relatively
independent dimension of health status that is related to depressive
symptoms, particularly anxiety and depressive ideation as well as
retardation and weight loss. Global disability may be associated with
impairment in initiation and perseveration and with late onset of
depression. These findings provide a basis for studies investigating
whether psychotherapy aimed at depressive ideation and rehabilitation
efforts focused on instrumental activities of daily living can improve the
outcome of geriatric depression.</abstract><cop>Washington, DC</cop><pub>American Psychiatric Publishing</pub><pmid>8659609</pmid><doi>10.1176/ajp.153.7.877</doi><tpages>9</tpages></addata></record> |
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ispartof | The American journal of psychiatry, 1996-07, Vol.153 (7), p.877-885 |
issn | 0002-953X 1535-7228 |
language | eng |
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source | MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996; Periodicals Index Online; Applied Social Sciences Index & Abstracts (ASSIA) |
subjects | Activities of Daily Living Age of Onset Aged Anxiety - psychology Biological and medical sciences Cognition Disorders - diagnosis Cognition Disorders - epidemiology Comorbidity Dementia - diagnosis Dementia - epidemiology Depression Depression - psychology Depressive Disorder - diagnosis Depressive Disorder - epidemiology Depressive Disorder - rehabilitation Disability Disability Evaluation Elderly people Female Geriatric Assessment - statistics & numerical data Geriatric psychology Geriatrics Health Status Indicators Humans Male Medical sciences Mental depression Older people Psychiatric Status Rating Scales Psychiatry Psychology. Psychoanalysis. Psychiatry Psychomotor Performance Psychopathology. Psychiatry Regression Analysis Severity of Illness Index Social Support Weight Loss |
title | Disability in geriatric depression |
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