Haemodynamic and metabolic responses of the lower limb after high intensity exercise in humans
This study assessed blood flow in the common femoral, superficial femoral and profunda femoris arteries, the effects of vasodilator metabolites and changes in blood pressure and pulse during recovery after high intensity exercise (Wingate test). Mean common femoral artery flow increased sevenfold in...
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| Veröffentlicht in: | Experimental physiology 1996-03, Vol.81 (2), p.173-187 |
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| creator | Hussain, ST Smith, RE Medbak, S Wood, RF Whipp, BJ |
| description | This study assessed blood flow in the common femoral, superficial femoral and profunda femoris arteries, the effects of vasodilator
metabolites and changes in blood pressure and pulse during recovery after high intensity exercise (Wingate test). Mean common
femoral artery flow increased sevenfold in response to the exercise. The subsequent decline in mean common femoral artery
flow was mono-exponential with a mean time constant of 19 min. The post-exercise increase in profunda femoris artery flow
(ninefold) was significantly greater than the superficial femoral artery flow (fourfold, P < 0.05). Systolic blood pressure
and heart rate decreased monotonically throughout recovery. In contrast, diastolic blood pressure showed a significant fall
below baseline at 3 min (P < 0.05) with a return to baseline at 60 min. The greatest drop below baseline (approximately 20
mmHg) occurred around 7 min. Lactate reached a maximum of 13.6 +/- 2.3 mmol -1 at 8 min (P < 0.05) and was still significantly
above baseline at 60 min. pH remained below 7.2 until 20 min of recovery. The results demonstrate that following high intensity
exercise, blood flow to the limbs appears to be controlled by complex interactions of various vaso-active metabolites, each
contributing proportionally more at different times during recovery. |
| doi_str_mv | 10.1113/expphysiol.1996.sp003923 |
| format | Article |
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metabolites and changes in blood pressure and pulse during recovery after high intensity exercise (Wingate test). Mean common
femoral artery flow increased sevenfold in response to the exercise. The subsequent decline in mean common femoral artery
flow was mono-exponential with a mean time constant of 19 min. The post-exercise increase in profunda femoris artery flow
(ninefold) was significantly greater than the superficial femoral artery flow (fourfold, P < 0.05). Systolic blood pressure
and heart rate decreased monotonically throughout recovery. In contrast, diastolic blood pressure showed a significant fall
below baseline at 3 min (P < 0.05) with a return to baseline at 60 min. The greatest drop below baseline (approximately 20
mmHg) occurred around 7 min. Lactate reached a maximum of 13.6 +/- 2.3 mmol -1 at 8 min (P < 0.05) and was still significantly
above baseline at 60 min. pH remained below 7.2 until 20 min of recovery. The results demonstrate that following high intensity
exercise, blood flow to the limbs appears to be controlled by complex interactions of various vaso-active metabolites, each
contributing proportionally more at different times during recovery.</description><identifier>ISSN: 0958-0670</identifier><identifier>EISSN: 1469-445X</identifier><identifier>DOI: 10.1113/expphysiol.1996.sp003923</identifier><identifier>PMID: 8845133</identifier><language>eng</language><publisher>England: The Physiological Society</publisher><subject>Adult ; Blood Flow Velocity ; Blood Pressure ; Catecholamines - blood ; Electrolytes - blood ; Ergometry ; Exercise - physiology ; Femoral Artery - physiology ; Heart Rate ; Hemodynamics ; Humans ; Kinetics ; Lactates - metabolism ; Lactic Acid ; Leg - physiology ; Male ; Vasodilation</subject><ispartof>Experimental physiology, 1996-03, Vol.81 (2), p.173-187</ispartof><rights>1996 The Physiological Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4343-58bc853bf8c2461920198bb79d4fdea6266141c317982b751c9e2916067b4d953</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1113%2Fexpphysiol.1996.sp003923$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1113%2Fexpphysiol.1996.sp003923$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8845133$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hussain, ST</creatorcontrib><creatorcontrib>Smith, RE</creatorcontrib><creatorcontrib>Medbak, S</creatorcontrib><creatorcontrib>Wood, RF</creatorcontrib><creatorcontrib>Whipp, BJ</creatorcontrib><title>Haemodynamic and metabolic responses of the lower limb after high intensity exercise in humans</title><title>Experimental physiology</title><addtitle>Exp Physiol</addtitle><description>This study assessed blood flow in the common femoral, superficial femoral and profunda femoris arteries, the effects of vasodilator
metabolites and changes in blood pressure and pulse during recovery after high intensity exercise (Wingate test). Mean common
femoral artery flow increased sevenfold in response to the exercise. The subsequent decline in mean common femoral artery
flow was mono-exponential with a mean time constant of 19 min. The post-exercise increase in profunda femoris artery flow
(ninefold) was significantly greater than the superficial femoral artery flow (fourfold, P < 0.05). Systolic blood pressure
and heart rate decreased monotonically throughout recovery. In contrast, diastolic blood pressure showed a significant fall
below baseline at 3 min (P < 0.05) with a return to baseline at 60 min. The greatest drop below baseline (approximately 20
mmHg) occurred around 7 min. Lactate reached a maximum of 13.6 +/- 2.3 mmol -1 at 8 min (P < 0.05) and was still significantly
above baseline at 60 min. pH remained below 7.2 until 20 min of recovery. The results demonstrate that following high intensity
exercise, blood flow to the limbs appears to be controlled by complex interactions of various vaso-active metabolites, each
contributing proportionally more at different times during recovery.</description><subject>Adult</subject><subject>Blood Flow Velocity</subject><subject>Blood Pressure</subject><subject>Catecholamines - blood</subject><subject>Electrolytes - blood</subject><subject>Ergometry</subject><subject>Exercise - physiology</subject><subject>Femoral Artery - physiology</subject><subject>Heart Rate</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Kinetics</subject><subject>Lactates - metabolism</subject><subject>Lactic Acid</subject><subject>Leg - physiology</subject><subject>Male</subject><subject>Vasodilation</subject><issn>0958-0670</issn><issn>1469-445X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUFv1DAQha0KVJbCT0DyCXHJ4rEdxz6iVcsiVSoHkHqq5TiTxiiJQ5zVNv-eRLu0N8TJ9sx7bzT-CKHAtgAgPuPTMDRzCrHdgjFqmwbGhOHigmxAKpNJmd-_Ihtmcp0xVbA35G1KvxgDwbS8JJdayxyE2JCHvcMuVnPvuuCp6yva4eTK2C6vEdMQ-4SJxppODdI2HnGkbehK6uppuTbhsaGhn7BPYZopPuHoQ8KlRJtD5_r0jryuXZvw_fm8Ij9vrn_s9tnt3ddvuy-3mZdCiizXpde5KGvtuVRgOAOjy7IwlawrdIorBRK8gMJoXhY5eIPcgFpWK2VlcnFFPp5yhzH-PmCabBeSx7Z1PcZDsoUGZrgxi_DTP4WgZMGAC71m6pPUjzGlEWs7jKFz42yB2ZWCfaFgVwr2L4XF-uE85VB2WD0bz9--9Hen_jG0OP93rr3-vl8LGjgU4mXpFcMxjGhPrhR9wGmZBpbbVfgHgCyqPQ</recordid><startdate>19960301</startdate><enddate>19960301</enddate><creator>Hussain, ST</creator><creator>Smith, RE</creator><creator>Medbak, S</creator><creator>Wood, RF</creator><creator>Whipp, BJ</creator><general>The Physiological Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>19960301</creationdate><title>Haemodynamic and metabolic responses of the lower limb after high intensity exercise in humans</title><author>Hussain, ST ; Smith, RE ; Medbak, S ; Wood, RF ; Whipp, BJ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4343-58bc853bf8c2461920198bb79d4fdea6266141c317982b751c9e2916067b4d953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Blood Flow Velocity</topic><topic>Blood Pressure</topic><topic>Catecholamines - blood</topic><topic>Electrolytes - blood</topic><topic>Ergometry</topic><topic>Exercise - physiology</topic><topic>Femoral Artery - physiology</topic><topic>Heart Rate</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Kinetics</topic><topic>Lactates - metabolism</topic><topic>Lactic Acid</topic><topic>Leg - physiology</topic><topic>Male</topic><topic>Vasodilation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hussain, ST</creatorcontrib><creatorcontrib>Smith, RE</creatorcontrib><creatorcontrib>Medbak, S</creatorcontrib><creatorcontrib>Wood, RF</creatorcontrib><creatorcontrib>Whipp, BJ</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hussain, ST</au><au>Smith, RE</au><au>Medbak, S</au><au>Wood, RF</au><au>Whipp, BJ</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Haemodynamic and metabolic responses of the lower limb after high intensity exercise in humans</atitle><jtitle>Experimental physiology</jtitle><addtitle>Exp Physiol</addtitle><date>1996-03-01</date><risdate>1996</risdate><volume>81</volume><issue>2</issue><spage>173</spage><epage>187</epage><pages>173-187</pages><issn>0958-0670</issn><eissn>1469-445X</eissn><abstract>This study assessed blood flow in the common femoral, superficial femoral and profunda femoris arteries, the effects of vasodilator
metabolites and changes in blood pressure and pulse during recovery after high intensity exercise (Wingate test). Mean common
femoral artery flow increased sevenfold in response to the exercise. The subsequent decline in mean common femoral artery
flow was mono-exponential with a mean time constant of 19 min. The post-exercise increase in profunda femoris artery flow
(ninefold) was significantly greater than the superficial femoral artery flow (fourfold, P < 0.05). Systolic blood pressure
and heart rate decreased monotonically throughout recovery. In contrast, diastolic blood pressure showed a significant fall
below baseline at 3 min (P < 0.05) with a return to baseline at 60 min. The greatest drop below baseline (approximately 20
mmHg) occurred around 7 min. Lactate reached a maximum of 13.6 +/- 2.3 mmol -1 at 8 min (P < 0.05) and was still significantly
above baseline at 60 min. pH remained below 7.2 until 20 min of recovery. The results demonstrate that following high intensity
exercise, blood flow to the limbs appears to be controlled by complex interactions of various vaso-active metabolites, each
contributing proportionally more at different times during recovery.</abstract><cop>England</cop><pub>The Physiological Society</pub><pmid>8845133</pmid><doi>10.1113/expphysiol.1996.sp003923</doi><tpages>15</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0958-0670 |
| ispartof | Experimental physiology, 1996-03, Vol.81 (2), p.173-187 |
| issn | 0958-0670 1469-445X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78109299 |
| source | Wiley-Blackwell Journals; MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Blood Flow Velocity Blood Pressure Catecholamines - blood Electrolytes - blood Ergometry Exercise - physiology Femoral Artery - physiology Heart Rate Hemodynamics Humans Kinetics Lactates - metabolism Lactic Acid Leg - physiology Male Vasodilation |
| title | Haemodynamic and metabolic responses of the lower limb after high intensity exercise in humans |
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